Version history

{
  "scope": "mouse vibrissal motor (vM1), primary somatosensory (vS1) and secondary somatosensory (S2) cortices",
  "claim_text": "LSPS connectivity-matrix mapping shows that mouse vibrissal M1, vS1 and S2 each have distinct laminar excitatory architectures: vM1 is dominated by an L2/3→upper-L5 descending pathway, while vS1 and S2 each carry strong L4→L3 ascending and L2/3→L5 descending pathways, with S2 additionally exhibiting L6↔L5B interactions.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1371/journal.pbio.1000572",
    "claim": "LSPS connectivity-matrix mapping shows that mouse vibrissal M1, vS1 and S2 each have distinct laminar excitatory architectures: vM1 is dominated by an L2/3→upper-L5 descending pathway, while vS1 and S2 each carry strong L4→L3 ascending and L2/3→L5 descending pathways, with S2 additionally exhibiting L6↔L5B interactions.",
    "cite_key": "Hooks2011",
    "evidence": "Glutamate-uncaging LSPS input maps across cortical depth in mouse vM1, vS1 and S2 coronal slices, summarized as area-specific neuron→neuron and layer→layer connectivity matrices.",
    "effect_size": "qualitative — area-specific laminar excitatory architecture across three whisker-related cortices",
    "text_access": "fulltext",
    "study_system": "mouse vibrissal motor (vM1), primary somatosensory (vS1) and secondary somatosensory (S2) cortices",
    "argument_role": "supporting",
    "replication_status": "independently_replicated",
    "claim_source_sentence": "vM1 contains a strong pathway from L2/3 to upper L5; that vS1 and S2 contain two strong pathways, corresponding to L4→L3 and L2/3→L5; and that S2 contains these plus pathways between L6 and L5B",
    "source_provenance_status": "ok",
    "replication_evidence_dois": [
      "10.1038/nn.2538"
    ],
    "effect_size_source_sentence": "our main findings were that vM1 contains a strong pathway from L2/3 to upper L5; that vS1 and S2 contain two strong pathways"
  },
  "section_id": "section_07",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_07_evidence_package.json",
  "effect_size": "qualitative — area-specific laminar excitatory architecture across three whisker-related cortices",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-07-celltype-motifs",
  "source_kind": "review_finding",
  "source_path": "evidence/section_07_evidence_package.json",
  "source_refs": [
    "paper:82e14b69-8c1b-41b8-b15b-f103a44caf3f"
  ],
  "source_span": "vM1 contains a strong pathway from L2/3 to upper L5; that vS1 and S2 contain two strong pathways, corresponding to L4→L3 and L2/3→L5; and that S2 contains these plus pathways between L6 and L5B",
  "study_system": "mouse vibrissal motor (vM1), primary somatosensory (vS1) and secondary somatosensory (S2) cortices",
  "evidence_refs": [
    {
      "ref": "paper:82e14b69-8c1b-41b8-b15b-f103a44caf3f"
    }
  ],
  "section_title": "7. Cell-type-specific E→E motifs in mouse — IT vs PT vs CT pyramidal projection classes; L5 thick-tufted recurrence; Patch-seq and Allen mouse-cortex taxonomy intersections; transcriptomic-type-specific connectivity",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Glutamate-uncaging LSPS input maps across cortical depth in mouse vM1, vS1 and S2 coronal slices, summarized as area-specific neuron→neuron and layer→layer connectivity matrices.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "independently_replicated",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-07-celltype-motifs",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_07_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}