Version history

{
  "scope": "mouse hippocampus CA1, VIP-eGFP, in vivo 2-photon Ca2+ imaging",
  "claim_text": "A subset of CA1 VIP+ interneurons projects long-range axons to subiculum and is recruited preferentially during quiet wakefulness rather than during theta-run/locomotion, contrasting with classical disinhibitory VIP cells.",
  "raw_fields": {
    "n": 3,
    "doi": "10.1038/s41467-018-07162-5",
    "claim": "A subset of CA1 VIP+ interneurons projects long-range axons to subiculum and is recruited preferentially during quiet wakefulness rather than during theta-run/locomotion, contrasting with classical disinhibitory VIP cells.",
    "title": null,
    "cite_key": "Francavilla2018a",
    "evidence": "Body, Results: in vivo two-photon calcium imaging of VIP+ interneurons in CA1 O/A of awake VIP-eGFP mice; combined with retrograde bead labelling from subiculum.",
    "effect_size": "28 VIP+ cells analyzed in detail across 409 locomotion and 356 immobility periods",
    "text_access": "fulltext",
    "study_system": "mouse hippocampus CA1, VIP-eGFP, in vivo 2-photon Ca2+ imaging",
    "_source_cluster": "cluster_02_development_lineage",
    "replication_status": "single-study",
    "_source_cluster_index": 1,
    "claim_source_sentence": "Functionally, VIP-LRP cells correspond to theta-off cells 31 , 32 as they decrease their activity during theta-run epochs associated with locomotion and exhibit high activity during quiet wakefulness.",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "Among 54 CA1 VIP+ interneurons imaged, 28 VIP+ cells were located within O/A and analyzed in detail during 409 locomotion and 356 immobility periods (10–15 periods/cell pooled from two independent imaging sessions of 5 min each/3 mice; Table S4 )."
  },
  "section_id": "section_03",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_03_evidence_package.json",
  "effect_size": "28 VIP+ cells analyzed in detail across 409 locomotion and 356 immobility periods",
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-03-development",
  "source_kind": "review_finding",
  "source_path": "evidence/section_03_evidence_package.json",
  "source_refs": [
    "paper:paper-c5dc6d520729"
  ],
  "source_span": "Functionally, VIP-LRP cells correspond to theta-off cells 31 , 32 as they decrease their activity during theta-run epochs associated with locomotion and exhibit high activity during quiet wakefulness.",
  "study_system": "mouse hippocampus CA1, VIP-eGFP, in vivo 2-photon Ca2+ imaging",
  "evidence_refs": [
    {
      "ref": "paper:paper-c5dc6d520729"
    }
  ],
  "section_title": "Developmental Origins and Postnatal Maturation",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "Body, Results: in vivo two-photon calcium imaging of VIP+ interneurons in CA1 O/A of awake VIP-eGFP mice; combined with retrograde bead labelling from subiculum.",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "single-study",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-03-development",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_03_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}