A subset of CA1 VIP+ interneurons projects long-range axons to subiculum and is…

{
  "n": 3,
  "doi": "10.1038/s41467-018-07162-5",
  "claim": "A subset of CA1 VIP+ interneurons projects long-range axons to subiculum and is recruited preferentially during quiet wakefulness rather than during theta-run/locomotion, contrasting with classical disinhibitory VIP cells.",
  "title": null,
  "cite_key": "Francavilla2018a",
  "evidence": "Body, Results: in vivo two-photon calcium imaging of VIP+ interneurons in CA1 O/A of awake VIP-eGFP mice; combined with retrograde bead labelling from subiculum.",
  "effect_size": "28 VIP+ cells analyzed in detail across 409 locomotion and 356 immobility periods",
  "text_access": "fulltext",
  "study_system": "mouse hippocampus CA1, VIP-eGFP, in vivo 2-photon Ca2+ imaging",
  "_source_cluster": "cluster_02_development_lineage",
  "replication_status": "single-study",
  "_source_cluster_index": 1,
  "claim_source_sentence": "Functionally, VIP-LRP cells correspond to theta-off cells 31 , 32 as they decrease their activity during theta-run epochs associated with locomotion and exhibit high activity during quiet wakefulness.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "Among 54 CA1 VIP+ interneurons imaged, 28 VIP+ cells were located within O/A and analyzed in detail during 409 locomotion and 356 immobility periods (10–15 periods/cell pooled from two independent imaging sessions of 5 min each/3 mice; Table S4 )."
}

[
  "paper:paper-c5dc6d520729"
]

[
  {
    "ref": "paper:paper-c5dc6d520729"
  }
]

{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}