Details

scope
mouse primary visual cortex (V1) layer 2/3, awake head-fixed, 2p holographic optogenetics
section_id
section_02
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_02_evidence_package.json
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-02-anatomy-primer
source_kind
review_finding
source_path
evidence/section_02_evidence_package.json
source_span
Selective holographic photoactivation of these 'IC-encoders' recreated the visual representation of ICs in V1 in the absence of any visual stimulus.
study_system
mouse primary visual cortex (V1) layer 2/3, awake head-fixed, 2p holographic optogenetics
section_title
2. Mouse-cortex anatomy primer — areal map, layer structure, projection-class nomenclature (IT / PT / CT), tools available for E→E dissection (paired patch, Cre lines, two-photon-targeted patch, optogenetics, EM reconstruction)
evidence_summary
Two-photon holographic optogenetics in awake mouse V1, combined with Neuropixels recording and mesoscale 2p Ca²⁺ imaging.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-02-anatomy-primer
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_02_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (5)
claim_text
Selective holographic photoactivation of mouse V1 pyramidal neurons that emergently encode illusory contours reproduces the V1 representation of illusory contours without any visual stimulus, demonstrating that local recurrent excitation among E neurons is sufficient to generate inference-related activity.
raw_fields
{
  "n": null,
  "doi": "10.1038/s41593-025-02055-5",
  "claim": "Selective holographic photoactivation of mouse V1 pyramidal neurons that emergently encode illusory contours reproduces the V1 representation of illusory contours without any visual stimulus, demonstrating that local recurrent excitation among E neurons is sufficient to generate inference-related activity.",
  "cite_key": "Shin2025b",
  "evidence": "Two-photon holographic optogenetics in awake mouse V1, combined with Neuropixels recording and mesoscale 2p Ca²⁺ imaging.",
  "effect_size": null,
  "text_access": "abstract_only",
  "study_system": "mouse primary visual cortex (V1) layer 2/3, awake head-fixed, 2p holographic optogenetics",
  "argument_role": "supporting",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "Selective holographic photoactivation of these 'IC-encoders' recreated the visual representation of ICs in V1 in the absence of any visual stimulus.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-d021eac95dc2"
]
evidence_refs
[
  {
    "ref": "paper:paper-d021eac95dc2"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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