Details
- scope
- genetically modified mice (PV-Δγ2), freely behaving, hippocampal recordings
- claim_text
- Synaptic inhibition onto PV+ interneurons is indispensable for theta oscillations and theta-gamma coupling but surprisingly not for gamma oscillations alone in hippocampus
- section_id
- section_10_evidence_package
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_10_evidence_package.json
- effect_size
- Theta rhythm strongly reduced in PV-Δγ2 mice; gamma oscillations not altered
- review_repo
- ComputationalReviewPV
- section_ref
- wiki_page:computationalreviewpv-10
- source_kind
- review_finding
- source_path
- evidence/section_10_evidence_package.json
- source_span
- These data indicate that synaptic inhibition onto PV+ interneurons is indispensable for theta- and its coupling to gamma oscillations but not for rhythmic gamma-activity in the hippocampus.
- study_system
- genetically modified mice (PV-Δγ2), freely behaving, hippocampal recordings
- section_title
- Oscillations and Network Dynamics: Gamma, Ripples, and Synchrony
- evidence_summary
- Synaptic inhibition onto PV+ interneurons is indispensable for theta oscillations and theta-gamma coupling but surprisingly not for gamma oscillations alone in hippocampus
- review_bundle_ref
- analysis_bundle:ab-e6261c8263e7
- replication_status
- replication_unknown
- review_package_ref
- analysis_bundle:ab-e6261c8263e7
- source_artifact_ref
- wiki_page:computationalreviewpv-10
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_10_evidence_package.json
- commit_sha
- df9fc7e8d455b084152c9d713558dae0013cef21
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (4)
- raw_fields
{ "n": 0, "doi": "10.1073/pnas.0813176106", "claim": "Synaptic inhibition onto PV+ interneurons is indispensable for theta oscillations and theta-gamma coupling but surprisingly not for gamma oscillations alone in hippocampus", "evidence": "Synaptic inhibition onto PV+ interneurons is indispensable for theta oscillations and theta-gamma coupling but surprisingly not for gamma oscillations alone in hippocampus", "effect_size": "Theta rhythm strongly reduced in PV-Δγ2 mice; gamma oscillations not altered", "text_access": "fulltext", "study_system": "genetically modified mice (PV-Δγ2), freely behaving, hippocampal recordings", "replication_status": "replication_unknown", "claim_source_sentence": "These data indicate that synaptic inhibition onto PV+ interneurons is indispensable for theta- and its coupling to gamma oscillations but not for rhythmic gamma-activity in the hippocampus.", "replication_evidence_dois": [], "effect_size_source_sentence": "Hippocampal local field potential and unit recordings in the CA1 area of freely behaving mice revealed that theta rhythm was strongly reduced in these mice." }- source_refs
[ "paper:paper-5b5d1f4b5090" ]
- evidence_refs
[ { "ref": "paper:paper-5b5d1f4b5090" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }