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- Live5/17/2026, 4:35:28 PM
0261e6a5d2ceContent snapshot
{ "scope": "genetically modified mice (PV-Δγ2), freely behaving, hippocampal recordings", "claim_text": "Synaptic inhibition onto PV+ interneurons is indispensable for theta oscillations and theta-gamma coupling but surprisingly not for gamma oscillations alone in hippocampus", "raw_fields": { "n": 0, "doi": "10.1073/pnas.0813176106", "claim": "Synaptic inhibition onto PV+ interneurons is indispensable for theta oscillations and theta-gamma coupling but surprisingly not for gamma oscillations alone in hippocampus", "evidence": "Synaptic inhibition onto PV+ interneurons is indispensable for theta oscillations and theta-gamma coupling but surprisingly not for gamma oscillations alone in hippocampus", "effect_size": "Theta rhythm strongly reduced in PV-Δγ2 mice; gamma oscillations not altered", "text_access": "fulltext", "study_system": "genetically modified mice (PV-Δγ2), freely behaving, hippocampal recordings", "replication_status": "replication_unknown", "claim_source_sentence": "These data indicate that synaptic inhibition onto PV+ interneurons is indispensable for theta- and its coupling to gamma oscillations but not for rhythmic gamma-activity in the hippocampus.", "replication_evidence_dois": [], "effect_size_source_sentence": "Hippocampal local field potential and unit recordings in the CA1 area of freely behaving mice revealed that theta rhythm was strongly reduced in these mice." }, "section_id": "section_10_evidence_package", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_10_evidence_package.json", "effect_size": "Theta rhythm strongly reduced in PV-Δγ2 mice; gamma oscillations not altered", "review_repo": "ComputationalReviewPV", "section_ref": "wiki_page:computationalreviewpv-10", "source_kind": "review_finding", "source_path": "evidence/section_10_evidence_package.json", "source_refs": [ "paper:paper-5b5d1f4b5090" ], "source_span": "These data indicate that synaptic inhibition onto PV+ interneurons is indispensable for theta- and its coupling to gamma oscillations but not for rhythmic gamma-activity in the hippocampus.", "study_system": "genetically modified mice (PV-Δγ2), freely behaving, hippocampal recordings", "evidence_refs": [ { "ref": "paper:paper-5b5d1f4b5090" } ], "section_title": "Oscillations and Network Dynamics: Gamma, Ripples, and Synchrony", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }, "evidence_summary": "Synaptic inhibition onto PV+ interneurons is indispensable for theta oscillations and theta-gamma coupling but surprisingly not for gamma oscillations alone in hippocampus", "review_bundle_ref": "analysis_bundle:ab-e6261c8263e7", "replication_status": "replication_unknown", "review_package_ref": "analysis_bundle:ab-e6261c8263e7", "source_artifact_ref": "wiki_page:computationalreviewpv-10", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_10_evidence_package.json", "commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }