Version history

{
  "scope": "awake mouse V1 L2/3 plus pulvinar thalamic input during visual prediction-error task",
  "claim_text": "Mouse V1 prediction-error signals are generated by a cooperative thalamocortical disinhibitory circuit: violating predictions with unexpected visual stimuli preferentially boosts responses of L2/3 V1 neurons most selective for that stimulus, demonstrating that prediction errors specifically amplify the unexpected input (rather than generating non-specific surprise signals) — implemented by a circuit involving cortically driven thalamic input and local disinhibition.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1038/s41586-024-07851-w",
    "claim": "Mouse V1 prediction-error signals are generated by a cooperative thalamocortical disinhibitory circuit: violating predictions with unexpected visual stimuli preferentially boosts responses of L2/3 V1 neurons most selective for that stimulus, demonstrating that prediction errors specifically amplify the unexpected input (rather than generating non-specific surprise signals) — implemented by a circuit involving cortically driven thalamic input and local disinhibition.",
    "cite_key": "Furutachi2024",
    "evidence": "Two-photon Ca²⁺ imaging + cell-type-specific optogenetic perturbations of mouse V1 L2/3 plus pulvinar thalamic input during prediction-error paradigm.",
    "effect_size": "qualitative — selective amplification of expected-stimulus-tuned neurons by thalamocortical disinhibition",
    "text_access": "fulltext",
    "study_system": "awake mouse V1 L2/3 plus pulvinar thalamic input during visual prediction-error task",
    "argument_role": "supporting",
    "replication_status": "single_study",
    "claim_source_sentence": "violating animals' predictions by an unexpected visual stimulus preferentially boosts responses of the layer 2/3 V1 neurons that are most selective for that stimulus. Prediction errors specifically amplify the unexpected visual input, rather than representing non-specific surprise or difference signals",
    "source_provenance_status": "ok",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "Prediction errors specifically amplify the unexpected visual input"
  },
  "section_id": "section_07",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_07_evidence_package.json",
  "effect_size": "qualitative — selective amplification of expected-stimulus-tuned neurons by thalamocortical disinhibition",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-07-celltype-motifs",
  "source_kind": "review_finding",
  "source_path": "evidence/section_07_evidence_package.json",
  "source_refs": [
    "paper:paper-41aa556ea384"
  ],
  "source_span": "violating animals' predictions by an unexpected visual stimulus preferentially boosts responses of the layer 2/3 V1 neurons that are most selective for that stimulus. Prediction errors specifically amplify the unexpected visual input, rather than representing non-specific surprise or difference signals",
  "study_system": "awake mouse V1 L2/3 plus pulvinar thalamic input during visual prediction-error task",
  "evidence_refs": [
    {
      "ref": "paper:paper-41aa556ea384"
    }
  ],
  "section_title": "7. Cell-type-specific E→E motifs in mouse — IT vs PT vs CT pyramidal projection classes; L5 thick-tufted recurrence; Patch-seq and Allen mouse-cortex taxonomy intersections; transcriptomic-type-specific connectivity",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Two-photon Ca²⁺ imaging + cell-type-specific optogenetic perturbations of mouse V1 L2/3 plus pulvinar thalamic input during prediction-error paradigm.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "single_study",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-07-celltype-motifs",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_07_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}