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- Live5/17/2026, 4:35:28 PM
799beca70cf1Content snapshot
{ "scope": "Detailed biophysical model of mouse primary motor cortex", "claim_text": "A multiscale, biophysically detailed model of mouse M1 with cell-type and laminar specificity predicts behavioral-state-dependent firing rates and LFP and yields low-dimensional latent dynamics.", "raw_fields": { "n": null, "doi": "10.1016/j.celrep.2023.112574", "claim": "A multiscale, biophysically detailed model of mouse M1 with cell-type and laminar specificity predicts behavioral-state-dependent firing rates and LFP and yields low-dimensional latent dynamics.", "cite_key": "DuraBernal2023", "evidence": "Mouse M1 model with >10,000 neurons and 30 million synapses, constrained by experimental connectivity and biophysics.", "effect_size": ">10,000 neurons and ~30 million synapses", "text_access": "abstract_only", "study_system": "Detailed biophysical model of mouse primary motor cortex", "argument_role": "supporting", "replication_status": "replication_unknown", "claim_source_sentence": "The model accurately predicts in vivo layer- and cell-type-specific responses (firing rates and LFP) associated with behavioral states (quiet wakefulness and movement) and experimental manipulations (noradrenaline receptor blockade and thalamus inactivation).", "source_provenance_status": "non_substring_match", "replication_evidence_dois": [], "effect_size_source_sentence": "We develop a multiscale, biophysically detailed model of mouse primary motor cortex (M1) with over 10,000 neurons and 30 million synapses." }, "section_id": "section_14", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_14_evidence_package.json", "effect_size": ">10,000 neurons and ~30 million synapses", "review_repo": "ComputationalReviewRecurrence", "section_ref": "wiki_page:computationalreviewrecurrence-14-predictive-coding", "source_kind": "review_finding", "source_path": "evidence/section_14_evidence_package.json", "source_refs": [ "paper:paper-39da47e849b2" ], "source_span": "The model accurately predicts in vivo layer- and cell-type-specific responses (firing rates and LFP) associated with behavioral states (quiet wakefulness and movement) and experimental manipulations (noradrenaline receptor blockade and thalamus inactivation).", "study_system": "Detailed biophysical model of mouse primary motor cortex", "evidence_refs": [ { "ref": "paper:paper-39da47e849b2" } ], "section_title": "14. Predictive-coding and dynamical-systems accounts — the role of recurrent excitatory feedback in error signalling, state estimation, and reservoir computing, evaluated against mouse data", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }, "evidence_summary": "Mouse M1 model with >10,000 neurons and 30 million synapses, constrained by experimental connectivity and biophysics.", "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9", "replication_status": "replication_unknown", "review_package_ref": "analysis_bundle:ab-d9c479db9be9", "source_artifact_ref": "wiki_page:computationalreviewrecurrence-14-predictive-coding", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_14_evidence_package.json", "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }