Details

scope
Detailed biophysical model of mouse primary motor cortex
claim_text
A multiscale, biophysically detailed model of mouse M1 with cell-type and laminar specificity predicts behavioral-state-dependent firing rates and LFP and yields low-dimensional latent dynamics.
section_id
section_14
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_14_evidence_package.json
effect_size
>10,000 neurons and ~30 million synapses
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-14-predictive-coding
source_kind
review_finding
source_path
evidence/section_14_evidence_package.json
study_system
Detailed biophysical model of mouse primary motor cortex
section_title
14. Predictive-coding and dynamical-systems accounts — the role of recurrent excitatory feedback in error signalling, state estimation, and reservoir computing, evaluated against mouse data
evidence_summary
Mouse M1 model with >10,000 neurons and 30 million synapses, constrained by experimental connectivity and biophysics.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-14-predictive-coding
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_14_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (5)
raw_fields
{
  "n": null,
  "doi": "10.1016/j.celrep.2023.112574",
  "claim": "A multiscale, biophysically detailed model of mouse M1 with cell-type and laminar specificity predicts behavioral-state-dependent firing rates and LFP and yields low-dimensional latent dynamics.",
  "cite_key": "DuraBernal2023",
  "evidence": "Mouse M1 model with >10,000 neurons and 30 million synapses, constrained by experimental connectivity and biophysics.",
  "effect_size": ">10,000 neurons and ~30 million synapses",
  "text_access": "abstract_only",
  "study_system": "Detailed biophysical model of mouse primary motor cortex",
  "argument_role": "supporting",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "The model accurately predicts in vivo layer- and cell-type-specific responses (firing rates and LFP) associated with behavioral states (quiet wakefulness and movement) and experimental manipulations (noradrenaline receptor blockade and thalamus inactivation).",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "We develop a multiscale, biophysically detailed model of mouse primary motor cortex (M1) with over 10,000 neurons and 30 million synapses."
}
source_refs
[
  "paper:paper-39da47e849b2"
]
source_span
The model accurately predicts in vivo layer- and cell-type-specific responses (firing rates and LFP) associated with behavioral states (quiet wakefulness and movement) and experimental manipulations (noradrenaline receptor blockade and thalamus inactivation).
evidence_refs
[
  {
    "ref": "paper:paper-39da47e849b2"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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