Version history

{
  "scope": "mouse; V1, visual cortex; whole-cell patch, optogenetics; Current biology : CB",
  "claim_text": "Here, we sought to determine whether higher order visual cortical areas lateromedial (LM), anterolateral (AL), posteromedial (PM), and anteromedial (AM) have specialized anatomical and physiological…",
  "raw_fields": {
    "n": null,
    "doi": "10.1016/j.cub.2021.09.042",
    "claim": "Here, we sought to determine whether higher order visual cortical areas lateromedial (LM), anterolateral (AL), posteromedial (PM), and anteromedial (AM) have specialized anatomical and physiological…",
    "cite_key": "Li2021a",
    "evidence": "Cortical visual processing transforms features of the external world into increasingly complex and specialized neuronal representations. These transformations arise in part through target-specific routing of information; however, within-area computations may also contribute to area-specific function. Here, we sought to determine whether higher order visual cortical areas lateromedial (LM), anterolateral (AL), posteromedial (PM), and anteromedial (AM) have specialized anatomical and physiological...",
    "effect_size": "In addition, we find that despite a lack of an overall difference in PV cell density across areas, there are some significant differences when separating by layers: PV cells in L6 are significantly more dense in AM compared to LM and AL, and PV cells in L5 are significantly denser in LM and AL versus AM (PV: one-way ANOVA with post hoc Tukey tests; L5 p=0.049, LM vs PM p=0.044; L6 p=0.008; LM vs PM p=0.011, AL vs PM p=0.037; n=8 mice).",
    "text_access": "fulltext",
    "study_system": "mouse; V1, visual cortex; whole-cell patch, optogenetics; Current biology : CB",
    "argument_role": "supporting",
    "replication_status": "single_study",
    "claim_source_sentence": "Here, we sought to determine whether higher order visual cortical areas lateromedial (LM), anterolateral (AL), posteromedial (PM), and anteromedial (AM) have specialized anatomical and physiological properties by using a combination of whole-cell recordings and optogenetic stimulation of primary visual cortex (V1) axons in vitro.",
    "source_provenance_status": "ok",
    "replication_evidence_dois": [],
    "claim_rewritten_from_source": true,
    "effect_size_source_sentence": "In addition, we find that despite a lack of an overall difference in PV cell density across areas, there are some significant differences when separating by layers: PV cells in L6 are significantly more dense in AM compared to LM and AL, and PV cells in L5 are significantly denser in LM and AL versus AM (PV: one-way ANOVA with post hoc Tukey tests; L5 p=0.049, LM vs PM p=0.044; L6 p=0.008; LM vs PM p=0.011, AL vs PM p=0.037; n=8 mice)."
  },
  "section_id": "section_09",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_09_evidence_package.json",
  "effect_size": "In addition, we find that despite a lack of an overall difference in PV cell density across areas, there are some significant differences when separating by layers: PV cells in L6 are significantly more dense in AM compared to LM and AL, and PV cells in L5 are significantly denser in LM and AL versus AM (PV: one-way ANOVA with post hoc Tukey tests; L5 p=0.049, LM vs PM p=0.044; L6 p=0.008; LM vs PM p=0.011, AL vs PM p=0.037; n=8 mice).",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-09-amplification-isn",
  "source_kind": "review_finding",
  "source_path": "evidence/section_09_evidence_package.json",
  "source_refs": [
    "paper:paper-21937e5a070f"
  ],
  "source_span": "Here, we sought to determine whether higher order visual cortical areas lateromedial (LM), anterolateral (AL), posteromedial (PM), and anteromedial (AM) have specialized anatomical and physiological properties by using a combination of whole-cell recordings and optogenetic stimulation of primary visual cortex (V1) axons in vitro.",
  "study_system": "mouse; V1, visual cortex; whole-cell patch, optogenetics; Current biology : CB",
  "evidence_refs": [
    {
      "ref": "paper:paper-21937e5a070f"
    }
  ],
  "section_title": "9. Physiological signature I — recurrent amplification of weak inputs in mouse cortex; balanced-amplification regimes; ISN operation",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Cortical visual processing transforms features of the external world into increasingly complex and specialized neuronal representations. These transformations arise in part through target-specific routing of information; however, within-area computations may also contribute to area-specific function. Here, we sought to determine whether higher order visual cortical areas lateromedial (LM), anterolateral (AL), posteromedial (PM), and anteromedial (AM) have specialized anatomical and physiological...",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "single_study",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-09-amplification-isn",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_09_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}