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- Live5/17/2026, 4:35:28 PM
8c9e652eb9ddContent snapshot
{ "scope": "mouse motor cortex L5B corticospinal vs corticostriatal pyramidal neurons", "claim_text": "Mouse motor cortex corticospinal pyramidal neurons display a class-specific intrinsic triad: relatively fast action potentials (half-width 0.65±0.13 ms) compared with neighboring corticostriatal IT-type neurons, nearly linear f-I relationships and regular repetitive firing — distinguishing the PT-type class from neighboring callosal IT cells.", "raw_fields": { "n": null, "doi": "10.1093/cercor/bhs184", "claim": "Mouse motor cortex corticospinal pyramidal neurons display a class-specific intrinsic triad: relatively fast action potentials (half-width 0.65±0.13 ms) compared with neighboring corticostriatal IT-type neurons, nearly linear f-I relationships and regular repetitive firing — distinguishing the PT-type class from neighboring callosal IT cells.", "cite_key": "Suter2013", "evidence": "Whole-cell current-clamp recordings of retrogradely identified corticospinal vs corticostriatal neurons in slices of young-adult mouse M1.", "effect_size": "AP half-width 0.65 ± 0.13 ms (corticospinal)", "text_access": "abstract_only", "study_system": "mouse motor cortex L5B corticospinal vs corticostriatal pyramidal neurons", "argument_role": "supporting", "replication_status": "replication_unknown", "claim_source_sentence": "Corticospinal neurons fired relatively fast action potentials (APs; width at half-maximum 0.65 ± 0.13 ms, mean ± standard deviation [SD]) compared with neighboring callosally projecting corticostriatal neurons.", "source_provenance_status": "non_substring_match", "replication_evidence_dois": [], "effect_size_source_sentence": "Corticospinal neurons fired relatively fast action potentials (APs; width at half-maximum 0.65 ± 0.13 ms, mean ± standard deviation [SD]) compared with neighboring callosally projecting corticostriatal neurons." }, "section_id": "section_02", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_02_evidence_package.json", "effect_size": "AP half-width 0.65 ± 0.13 ms (corticospinal)", "review_repo": "ComputationalReviewRecurrence", "section_ref": "wiki_page:computationalreviewrecurrence-02-anatomy-primer", "source_kind": "review_finding", "source_path": "evidence/section_02_evidence_package.json", "source_refs": [ "paper:paper-8d1d6c42c552" ], "source_span": "Corticospinal neurons fired relatively fast action potentials (APs; width at half-maximum 0.65 ± 0.13 ms, mean ± standard deviation [SD]) compared with neighboring callosally projecting corticostriatal neurons.", "study_system": "mouse motor cortex L5B corticospinal vs corticostriatal pyramidal neurons", "evidence_refs": [ { "ref": "paper:paper-8d1d6c42c552" } ], "section_title": "2. Mouse-cortex anatomy primer — areal map, layer structure, projection-class nomenclature (IT / PT / CT), tools available for E→E dissection (paired patch, Cre lines, two-photon-targeted patch, optogenetics, EM reconstruction)", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }, "evidence_summary": "Whole-cell current-clamp recordings of retrogradely identified corticospinal vs corticostriatal neurons in slices of young-adult mouse M1.", "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9", "replication_status": "replication_unknown", "review_package_ref": "analysis_bundle:ab-d9c479db9be9", "source_artifact_ref": "wiki_page:computationalreviewrecurrence-02-anatomy-primer", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_02_evidence_package.json", "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }