Mouse motor cortex corticospinal pyramidal neurons display a class-specific int…

Mouse motor cortex corticospinal pyramidal neurons display a class-specific intrinsic triad: relatively fast action potentials (half-width 0.65±0.13 ms) compared with neighboring corticostriatal IT-type neurons, nearly linear f-I relationships and regular repetitive firing — distinguishing the PT-type class from neighboring callosal IT cells.

{
  "n": null,
  "doi": "10.1093/cercor/bhs184",
  "claim": "Mouse motor cortex corticospinal pyramidal neurons display a class-specific intrinsic triad: relatively fast action potentials (half-width 0.65±0.13 ms) compared with neighboring corticostriatal IT-type neurons, nearly linear f-I relationships and regular repetitive firing — distinguishing the PT-type class from neighboring callosal IT cells.",
  "cite_key": "Suter2013",
  "evidence": "Whole-cell current-clamp recordings of retrogradely identified corticospinal vs corticostriatal neurons in slices of young-adult mouse M1.",
  "effect_size": "AP half-width 0.65 ± 0.13 ms (corticospinal)",
  "text_access": "abstract_only",
  "study_system": "mouse motor cortex L5B corticospinal vs corticostriatal pyramidal neurons",
  "argument_role": "supporting",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "Corticospinal neurons fired relatively fast action potentials (APs; width at half-maximum 0.65 ± 0.13 ms, mean ± standard deviation [SD]) compared with neighboring callosally projecting corticostriatal neurons.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "Corticospinal neurons fired relatively fast action potentials (APs; width at half-maximum 0.65 ± 0.13 ms, mean ± standard deviation [SD]) compared with neighboring callosally projecting corticostriatal neurons."
}

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