Version history

{
  "scope": "mouse VISp; standardized intracellular recordings + biocytin reconstruction",
  "claim_text": "Mouse VISp neurons partition into 17 distinct intrinsic electrophysiological types (e-types) that differ across firing-pattern descriptors (adapting, irregular, transient), AP shape, subthreshold properties (membrane time constant, sag), and f–I curve location/shape.",
  "raw_fields": {
    "n": null,
    "doi": "10.1038/s41593-019-0417-0",
    "claim": "Mouse VISp neurons partition into 17 distinct intrinsic electrophysiological types (e-types) that differ across firing-pattern descriptors (adapting, irregular, transient), AP shape, subthreshold properties (membrane time constant, sag), and f–I curve location/shape.",
    "title": null,
    "cite_key": "Gouwens2019",
    "evidence": "standardized current-clamp recordings of >1,800 mouse VISp neurons; unsupervised clustering on AP and f–I features",
    "effect_size": "17 e-types identified",
    "text_access": "fulltext",
    "study_system": "mouse VISp; standardized intracellular recordings + biocytin reconstruction",
    "_source_cluster": "cluster_04_intrinsic_electrophysiology",
    "replication_status": "replicated",
    "_source_cluster_index": 30,
    "claim_source_sentence": "Specific e-types differed from each other across a variety of characteristics, including firing patterns (e.g., adapting, irregular, transient), AP shape, subthreshold properties (membrane time constant, sag), and f-I curve location and shape.",
    "replication_evidence_dois": [
      "10.1016/j.cell.2020.09.057"
    ],
    "effect_size_source_sentence": "We next examined basic electrophysiological characteristics of the 17 identified e-types, such as the AP shape, the estimated membrane capacitance and input resistance, the average f-I curve, and the coefficient of variation of the ISI durations (CV ISI, Fig."
  },
  "section_id": "section_05",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json",
  "effect_size": "17 e-types identified",
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-05-electrophysiology",
  "source_kind": "review_finding",
  "source_path": "evidence/section_05_evidence_package.json",
  "source_refs": [
    "paper:paper-b9e0351c6ddd"
  ],
  "source_span": "Specific e-types differed from each other across a variety of characteristics, including firing patterns (e.g., adapting, irregular, transient), AP shape, subthreshold properties (membrane time constant, sag), and f-I curve location and shape.",
  "study_system": "mouse VISp; standardized intracellular recordings + biocytin reconstruction",
  "evidence_refs": [
    {
      "ref": "paper:paper-b9e0351c6ddd"
    }
  ],
  "section_title": "Intrinsic Electrophysiology",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "standardized current-clamp recordings of >1,800 mouse VISp neurons; unsupervised clustering on AP and f–I features",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "replicated",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-05-electrophysiology",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}