- claim_text
A biologically-motivated multi-area cortical microcircuit model implements error backpropagation with populations of pyramidal representation neurons and error neurons under bio-plausible local and inter-area connectivity, with cortical L2/3 pyramidal cells functioning as error-coding neurons consistent with experimental observations across visual, visuomotor, motor and auditory cortices.
- raw_fields
{
"n": 0,
"doi": "10.1371/journal.pcbi.1014164",
"claim": "A biologically-motivated multi-area cortical microcircuit model implements error backpropagation with populations of pyramidal representation neurons and error neurons under bio-plausible local and inter-area connectivity, with cortical L2/3 pyramidal cells functioning as error-coding neurons consistent with experimental observations across visual, visuomotor, motor and auditory cortices.",
"cite_key": "Max2026",
"evidence": "Theory paper that maps backpropagation to mouse-cortex E→E microcircuits — addresses cluster_14 synthesis topic on which computational accounts the empirical record supports.",
"effect_size": null,
"text_access": "fulltext",
"study_system": "Multi-area cortical microcircuit model with bio-plausible connectivity (rodent/primate visual cortex literature)",
"argument_role": "supporting",
"replication_status": "single-study",
"claim_source_sentence": "In particular, experimental findings suggest that cortical layer 2/3 (L2/3) pyramidal cells (PYR) function as error coding neurons, with evidence across many cortical areas, e.g., visual areas [ 4 , 13 – 16 ], visuomotor [ 17 ], motor [ 18 ], auditory [ 19 ].",
"source_provenance_status": "ok",
"replication_evidence_dois": [],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-395a8efaf26b"
]
- source_span
In particular, experimental findings suggest that cortical layer 2/3 (L2/3) pyramidal cells (PYR) function as error coding neurons, with evidence across many cortical areas, e.g., visual areas [ 4 , 13 – 16 ], visuomotor [ 17 ], motor [ 18 ], auditory [ 19 ].
- evidence_refs
[
{
"ref": "paper:paper-395a8efaf26b"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}