Version history

{
  "scope": "Multi-area cortical microcircuit model with bio-plausible connectivity (rodent/primate visual cortex literature)",
  "claim_text": "A biologically-motivated multi-area cortical microcircuit model implements error backpropagation with populations of pyramidal representation neurons and error neurons under bio-plausible local and inter-area connectivity, with cortical L2/3 pyramidal cells functioning as error-coding neurons consistent with experimental observations across visual, visuomotor, motor and auditory cortices.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1371/journal.pcbi.1014164",
    "claim": "A biologically-motivated multi-area cortical microcircuit model implements error backpropagation with populations of pyramidal representation neurons and error neurons under bio-plausible local and inter-area connectivity, with cortical L2/3 pyramidal cells functioning as error-coding neurons consistent with experimental observations across visual, visuomotor, motor and auditory cortices.",
    "cite_key": "Max2026",
    "evidence": "Theory paper that maps backpropagation to mouse-cortex E→E microcircuits — addresses cluster_14 synthesis topic on which computational accounts the empirical record supports.",
    "effect_size": null,
    "text_access": "fulltext",
    "study_system": "Multi-area cortical microcircuit model with bio-plausible connectivity (rodent/primate visual cortex literature)",
    "argument_role": "supporting",
    "replication_status": "single-study",
    "claim_source_sentence": "In particular, experimental findings suggest that cortical layer 2/3 (L2/3) pyramidal cells (PYR) function as error coding neurons, with evidence across many cortical areas, e.g., visual areas [ 4 , 13 – 16 ], visuomotor [ 17 ], motor [ 18 ], auditory [ 19 ].",
    "source_provenance_status": "ok",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": null
  },
  "section_id": "section_16",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_16_evidence_package.json",
  "effect_size": null,
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-16-synthesis",
  "source_kind": "review_finding",
  "source_path": "evidence/section_16_evidence_package.json",
  "source_refs": [
    "paper:paper-395a8efaf26b"
  ],
  "source_span": "In particular, experimental findings suggest that cortical layer 2/3 (L2/3) pyramidal cells (PYR) function as error coding neurons, with evidence across many cortical areas, e.g., visual areas [ 4 , 13 – 16 ], visuomotor [ 17 ], motor [ 18 ], auditory [ 19 ].",
  "study_system": "Multi-area cortical microcircuit model with bio-plausible connectivity (rodent/primate visual cortex literature)",
  "evidence_refs": [
    {
      "ref": "paper:paper-395a8efaf26b"
    }
  ],
  "section_title": "16. Synthesis — which computational claims the mouse-cortex E→E empirical record actually supports, where the bottleneck observations are, and what an inhibition-free, single-species, basic-research analytic framing misses",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Theory paper that maps backpropagation to mouse-cortex E→E microcircuits — addresses cluster_14 synthesis topic on which computational accounts the empirical record supports.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "single-study",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-16-synthesis",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_16_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}