Version history

{
  "scope": "compartmental pyramidal model",
  "claim_text": "Early theoretical analysis of cortical inhibitory subtype division-of-labor (PV vs SST vs VIP) establishes that compartment-specific inhibition supports differential gain control on dendrites vs soma.",
  "raw_fields": {
    "n": null,
    "id": "cluster_11_finding_105",
    "doi": "10.1073/pnas.0305337101",
    "pmid": "14742867",
    "year": "2004",
    "claim": "Early theoretical analysis of cortical inhibitory subtype division-of-labor (PV vs SST vs VIP) establishes that compartment-specific inhibition supports differential gain control on dendrites vs soma.",
    "pmcid": "PMC337059",
    "title": "Division of labor among distinct subtypes of inhibitory neurons in a cortical microcircuit of working memory.",
    "authors": "Wang XJ, Tegnér J, Constantinidis C, Goldman-Rakic PS.",
    "journal": "Proceedings of the National Academy of Sciences of the United States of America",
    "cite_key": "Wang2004a",
    "evidence": "Compartmental neuron model with PV-soma vs SOM-dendrite synapses; gain control quantified separately.",
    "effect_size": null,
    "text_access": "abstract_only",
    "study_system": "compartmental pyramidal model",
    "_source_cluster": "cluster_11_computational_models",
    "replication_status": "replicated_independent",
    "_collapsed_provenance": [
      {
        "doi": "10.1073/pnas.0305337101",
        "claim": "In a model designed for spatial working memory, stimulus tuning of persistent activity arises from the concerted action of widespread inhibition mediated by perisoma-targeting (parvalbumin-containing) interneurons and localized disinhibition of pyramidal cells via interneuron-targeting (calretinin-containing) interneurons.",
        "source_cluster": "cluster_06_disinhibition_circuit",
        "source_cluster_index": 74
      }
    ],
    "_source_cluster_index": 104,
    "claim_source_sentence": "In a model designed for spatial working memory, stimulus tuning of persistent activity arises from the concerted action of widespread inhibition mediated by perisoma-targeting (parvalbumin-containing) interneurons and localized disinhibition of pyramidal cells via interneuron-targeting (calretinin-containing) interneurons.",
    "replication_evidence_dois": [
      "10.7554/elife.55130",
      "10.1523/jneurosci.1369-21.2021",
      "10.1038/s41598-017-01830-0",
      "10.1371/journal.pcbi.1013306",
      "10.1016/j.neuron.2021.11.016"
    ],
    "effect_size_source_sentence": null
  },
  "section_id": "section_12",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json",
  "effect_size": null,
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-12-computational-models",
  "source_kind": "review_finding",
  "source_path": "evidence/section_12_evidence_package.json",
  "source_refs": [
    "paper:paper-4ced38bcaa48"
  ],
  "source_span": "In a model designed for spatial working memory, stimulus tuning of persistent activity arises from the concerted action of widespread inhibition mediated by perisoma-targeting (parvalbumin-containing) interneurons and localized disinhibition of pyramidal cells via interneuron-targeting (calretinin-containing) interneurons.",
  "study_system": "compartmental pyramidal model",
  "evidence_refs": [
    {
      "ref": "paper:paper-4ced38bcaa48"
    }
  ],
  "section_title": "Computational Models of VIP Circuit Function",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "Compartmental neuron model with PV-soma vs SOM-dendrite synapses; gain control quantified separately.",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "replicated_independent",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-12-computational-models",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}