- claim_text
Goal-directed behavior is hierarchically organized in interconnected cortico-basal ganglia loops, where a limbic-affective prefrontal-ventral striatal loop controls action selection in a dorsomedial prefrontal-striatal loop, which in turn regulates sensorimotor-dorsolateral striatal circuits, with frontal corticothalamic circuits initiating and temporally organizing nested memory consolidation activities.
- raw_fields
{
"n": null,
"doi": "10.1002/hipo.23167",
"claim": "Goal-directed behavior is hierarchically organized in interconnected cortico-basal ganglia loops, where a limbic-affective prefrontal-ventral striatal loop controls action selection in a dorsomedial prefrontal-striatal loop, which in turn regulates sensorimotor-dorsolateral striatal circuits, with frontal corticothalamic circuits initiating and temporally organizing nested memory consolidation activities.",
"cite_key": "Rusu2019",
"evidence": "This is a review/synthesis paper integrating findings on prefrontal cortex, hippocampus, striatum, and dopaminergic mesencephalon in relation to goal-directed versus habitual behavior and model-based versus model-free learning frameworks.",
"effect_size": null,
"text_access": "abstract_only",
"study_system": "mammalian cortico-basal ganglia-thalamo-cortical circuits (review)",
"source_cluster_id": "cluster_01",
"replication_status": "novel",
"claim_source_sentence": "We hypothesize that goal-directed behavior is hierarchically organized in interconnected cortico-basal ganglia loops, where a limbic-affective prefrontal-ventral striatal loop controls action selection in a dorsomedial prefrontal-striatal loop, which in turn regulates activity in sensorimotor-dorsolateral striatal circuits.",
"replication_evidence_dois": [],
"effect_size_source_sentence": null
}- source_refs
[
"paper:paper-b18ec9a61e77"
]
- source_span
We hypothesize that goal-directed behavior is hierarchically organized in interconnected cortico-basal ganglia loops, where a limbic-affective prefrontal-ventral striatal loop controls action selection in a dorsomedial prefrontal-striatal loop, which in turn regulates activity in sensorimotor-dorsolateral striatal circuits.
- evidence_refs
[
{
"ref": "paper:paper-b18ec9a61e77"
}
]- source_policy
{
"mode": "public_source_pointer_with_short_context",
"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}