In mouse prelimbic cortex (PL), L5 cortico-PAG projection neurons receive stron…

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scope: mouse prelimbic cortex L2 and L5 cortico-PAG projection neurons
claim_text: In mouse prelimbic cortex (PL), L5 cortico-PAG projection neurons receive strong descending intracortical input from L2 — defining a translaminar L2→L5 excitatory pathway in PL.
section_id: section_04
source_url: https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json
effect_size: strong L2→L5 descending input
review_repo: ComputationalReviewRecurrence
section_ref: wiki_page:computationalreviewrecurrence-04-translaminar
source_kind: review_finding
source_path: evidence/section_04_evidence_package.json
source_span: Using laser-scanning photostimulation of caged glutamate, we show that L5 PL-CP neurons receive strong descending input from L2.
study_system: mouse prelimbic cortex L2 and L5 cortico-PAG projection neurons
section_title: 4. Translaminar excitatory loops in mouse — L4→L2/3→L5→L6→L4 within the column; asymmetry of forward and backward intracortical projections
evidence_summary: Laser-scanning photostimulation of caged glutamate with whole-cell recordings of retrogradely labeled L5 PL-CP neurons.
review_bundle_ref: analysis_bundle:ab-d9c479db9be9
replication_status: replication_unknown
review_package_ref: analysis_bundle:ab-d9c479db9be9
source_artifact_ref: wiki_page:computationalreviewrecurrence-04-translaminar
origin_url: https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_04_evidence_package.json
commit_sha: 79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by: persona-jerome-lecoq-gbo-neuroscience
repository_url: https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence

Raw fields (4)

raw_fields

{
  "n": 0,
  "doi": "10.1523/eneuro.0002-16.2016",
  "claim": "In mouse prelimbic cortex (PL), L5 cortico-PAG projection neurons receive strong descending intracortical input from L2 — defining a translaminar L2→L5 excitatory pathway in PL.",
  "cite_key": "Cheriyan2016",
  "evidence": "Laser-scanning photostimulation of caged glutamate with whole-cell recordings of retrogradely labeled L5 PL-CP neurons.",
  "effect_size": "strong L2→L5 descending input",
  "text_access": "fulltext",
  "study_system": "mouse prelimbic cortex L2 and L5 cortico-PAG projection neurons",
  "argument_role": "supporting",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "Using laser-scanning photostimulation of caged glutamate, we show that L5 PL-CP neurons receive strong descending input from L2.",
  "source_provenance_status": "ok",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}

source_refs

[
  "paper:paper-e4ee2cb853fa"
]

evidence_refs

[
  {
    "ref": "paper:paper-e4ee2cb853fa"
  }
]

source_policy

{
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  "notes": [
    "Local review repositories are read-only inputs.",
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  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

In mouse prelimbic cortex (PL), L5 cortico-PAG projection neurons receive stron…

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