Details
- scope
- rat/mouse hippocampus CA1 and CA3, in vivo
- claim_text
- Axo-axonic cells are inhibited during sharp-wave ripples while PV basket cells strongly increase firing, demonstrating distinct roles of PV+ subtypes in hippocampal network states
- section_id
- section_09_evidence_package
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_09_evidence_package.json
- effect_size
- Axo-axonic cells are inhibited during sharp-wave ripples while PV basket cells strongly increase firing, demonstrating distinct roles of PV+ subtypes in hippocampal network states
- review_repo
- ComputationalReviewPV
- section_ref
- wiki_page:computationalreviewpv-09
- source_kind
- review_finding
- source_path
- evidence/section_09_evidence_package.json
- study_system
- rat/mouse hippocampus CA1 and CA3, in vivo
- section_title
- Brain Region and Layer Context: Beyond Primary Sensory Cortex
- evidence_summary
- Axo-axonic cells are inhibited during sharp-wave ripples while PV basket cells strongly increase firing, demonstrating distinct roles of PV+ subtypes in hippocampal network states
- review_bundle_ref
- analysis_bundle:ab-e6261c8263e7
- replication_status
- independently_replicated
- review_package_ref
- analysis_bundle:ab-e6261c8263e7
- source_artifact_ref
- wiki_page:computationalreviewpv-09
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_09_evidence_package.json
- commit_sha
- df9fc7e8d455b084152c9d713558dae0013cef21
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewPV
Raw fields (5)
- raw_fields
{ "n": 0, "doi": "10.1098/rstb.2012.0518", "claim": "Axo-axonic cells are inhibited during sharp-wave ripples while PV basket cells strongly increase firing, demonstrating distinct roles of PV+ subtypes in hippocampal network states", "evidence": "Axo-axonic cells are inhibited during sharp-wave ripples while PV basket cells strongly increase firing, demonstrating distinct roles of PV+ subtypes in hippocampal network states", "effect_size": "Axo-axonic cells are inhibited during sharp-wave ripples while PV basket cells strongly increase firing, demonstrating distinct roles of PV+ subtypes in hippocampal network states", "text_access": "fulltext", "study_system": "rat/mouse hippocampus CA1 and CA3, in vivo", "replication_status": "independently_replicated", "claim_source_sentence": "Axo-axonic cells are inhibited during SWRs, when many pyramidal cells fire synchronously. This dual inverse correlation demonstrates the key inhibitory role of axo-axonic cells. Parvalbumin-expressing basket cells fire phase locked to field gamma activity in both CA1 and CA3, and also strongly increase firing during SWRs, together with dendrite-innervating bistratified cells, phasing pyramidal cell discharge.", "replication_evidence_dois": [ "10.1523/jneurosci.4104-10.2010", "10.1073/pnas.1210929109" ], "effect_size_source_sentence": "Axo-axonic cells are inhibited during SWRs, when many pyramidal cells fire synchronously. This dual inverse correlation demonstrates the key inhibitory role of axo-axonic cells. Parvalbumin-expressing basket cells fire phase locked to field gamma activity in both CA1 and CA3, and also strongly increase firing during SWRs, together with dendrite-innervating bistratified cells, phasing pyramidal cell discharge." }- source_refs
[ "paper:paper-12b8963c5eea" ]
- source_span
Axo-axonic cells are inhibited during SWRs, when many pyramidal cells fire synchronously. This dual inverse correlation demonstrates the key inhibitory role of axo-axonic cells. Parvalbumin-expressing basket cells fire phase locked to field gamma activity in both CA1 and CA3, and also strongly increase firing during SWRs, together with dendrite-innervating bistratified cells, phasing pyramidal cell discharge.
- evidence_refs
[ { "ref": "paper:paper-12b8963c5eea" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }