Mouse barrel cortex L6 is organized into discrete infrabarrels: corticothalamic…

{
  "n": 0,
  "doi": "10.1016/j.celrep.2017.11.049",
  "claim": "Mouse barrel cortex L6 is organized into discrete infrabarrels: corticothalamic (CT) neurons and their local axons cluster within infrabarrels, while corticocortical (CC) neurons are densest between them.",
  "cite_key": "Crandall2017",
  "evidence": "Cell-type-specific labelling in Ntsr1-Cre mice and optogenetic mapping of thalamic input onto CT and CC L6 neurons.",
  "effect_size": "CT cells received much weaker thalamic inputs than CC cells (qualitative).",
  "text_access": "fulltext",
  "study_system": "Mouse barrel cortex; Ntsr1-Cre cell-type-specific labelling; in vitro optogenetic input mapping and intrinsic property measurements in L6 CT vs CC neurons",
  "argument_role": "supporting",
  "replication_status": "single_study",
  "claim_source_sentence": "Using the cell-type-specific Ntsr1-Cre mouse line, we found that L6 contains infrabarrels, readily identifiable units that align with the L4 barrels. Corticothalamic (CT) neurons and their local axons cluster within the infrabarrels, whereas corticocortical (CC) neurons are densest between infrabarrels.",
  "source_provenance_status": "ok",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "CC cells received robust input from somatosensory thalamic nuclei, whereas CT cells received much weaker thalamic inputs."
}

[
  "paper:paper-78f81bfb11b4"
]

Using the cell-type-specific Ntsr1-Cre mouse line, we found that L6 contains infrabarrels, readily identifiable units that align with the L4 barrels. Corticothalamic (CT) neurons and their local axons cluster within the infrabarrels, whereas corticocortical (CC) neurons are densest between infrabarrels.

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