Details

scope
Long-Term Personalized Adaptive Deep Brain Stimulation in Parkinson Disease: A Nonrandomized Clinical Trial.
claim_text
Conclusions and Relevance In this study, long-term aDBS was tolerable, effective, and safe in people with PD who were previously stable while receiving cDBS.
section_id
section_14
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_14_evidence_package.json
effect_size
97.5%
review_repo
ComputationalReviewLoops
section_ref
wiki_page:computationalreviewloops-14
source_kind
review_finding
source_path
evidence/section_14_evidence_package.json
source_span
Conclusions and Relevance In this study, long-term aDBS was tolerable, effective, and safe in people with PD who were previously stable while receiving cDBS.
study_system
Long-Term Personalized Adaptive Deep Brain Stimulation in Parkinson Disease: A Nonrandomized Clinical Trial.
section_title
Loop Dysfunction in Neurological and Psychiatric Disease
evidence_summary
(, 2025); Bronte-Stewart HM, Beudel M, Ostrem JL, Little S, Almeida L, Ramirez-Zamora A, Fasano A, Hassell T, Mitchell KT, Moro E, Gostkowski M, Chattree G, de Bie RMA, de Neeling M, Piña-Fuentes D, Swinnen B,
review_bundle_ref
analysis_bundle:ab-d49e54403ef9
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-d49e54403ef9
source_artifact_ref
wiki_page:computationalreviewloops-14
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_14_evidence_package.json
commit_sha
0632aae8abc141909207fe91f6349b9e36489c3b
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (4)
raw_fields
{
  "n": null,
  "doi": "10.1001/jamaneurol.2025.2781",
  "claim": "Conclusions and Relevance In this study, long-term aDBS was tolerable, effective, and safe in people with PD who were previously stable while receiving cDBS.",
  "cite_key": "Bronte2025",
  "evidence": " (, 2025); Bronte-Stewart HM, Beudel M, Ostrem JL, Little S, Almeida L, Ramirez-Zamora A, Fasano A, Hassell T, Mitchell KT, Moro E, Gostkowski M, Chattree G, de Bie RMA, de Neeling M, Piña-Fuentes D, Swinnen B, ",
  "effect_size": "97.5%",
  "text_access": "fulltext",
  "study_system": "Long-Term Personalized Adaptive Deep Brain Stimulation in Parkinson Disease: A Nonrandomized Clinical Trial.",
  "source_cluster_id": "cluster_13",
  "replication_status": "replication_unknown",
  "claim_source_sentence": "Conclusions and Relevance In this study, long-term aDBS was tolerable, effective, and safe in people with PD who were previously stable while receiving cDBS.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "The post hoc analysis (−2 hour per day performance threshold) primary end point was also met: 91% of participants receiving DT-aDBS (exact 97.5% lower confidence limit, 75.6%; n = 40) and 79% of participants receiving ST-aDBS (exact 97.5% lower confidence limit, 59.4%; n = 35) had comparable on-time to cDBS (both P < .001)."
}
source_refs
[
  "paper:paper-8402e4affac7"
]
evidence_refs
[
  {
    "ref": "paper:paper-8402e4affac7"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}

Voting as anonymous. Sign in to attribute your signals.

tokens

Replication

No replications yet

Discussion

Posting anonymously. Sign in for attribution.

No comments yet — be the first.