Version history

{
  "scope": "Long-Term Personalized Adaptive Deep Brain Stimulation in Parkinson Disease: A Nonrandomized Clinical Trial.",
  "claim_text": "Conclusions and Relevance In this study, long-term aDBS was tolerable, effective, and safe in people with PD who were previously stable while receiving cDBS.",
  "raw_fields": {
    "n": null,
    "doi": "10.1001/jamaneurol.2025.2781",
    "claim": "Conclusions and Relevance In this study, long-term aDBS was tolerable, effective, and safe in people with PD who were previously stable while receiving cDBS.",
    "cite_key": "Bronte2025",
    "evidence": " (, 2025); Bronte-Stewart HM, Beudel M, Ostrem JL, Little S, Almeida L, Ramirez-Zamora A, Fasano A, Hassell T, Mitchell KT, Moro E, Gostkowski M, Chattree G, de Bie RMA, de Neeling M, Piña-Fuentes D, Swinnen B, ",
    "effect_size": "97.5%",
    "text_access": "fulltext",
    "study_system": "Long-Term Personalized Adaptive Deep Brain Stimulation in Parkinson Disease: A Nonrandomized Clinical Trial.",
    "source_cluster_id": "cluster_13",
    "replication_status": "replication_unknown",
    "claim_source_sentence": "Conclusions and Relevance In this study, long-term aDBS was tolerable, effective, and safe in people with PD who were previously stable while receiving cDBS.",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "The post hoc analysis (−2 hour per day performance threshold) primary end point was also met: 91% of participants receiving DT-aDBS (exact 97.5% lower confidence limit, 75.6%; n = 40) and 79% of participants receiving ST-aDBS (exact 97.5% lower confidence limit, 59.4%; n = 35) had comparable on-time to cDBS (both P < .001)."
  },
  "section_id": "section_14",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_14_evidence_package.json",
  "effect_size": "97.5%",
  "review_repo": "ComputationalReviewLoops",
  "section_ref": "wiki_page:computationalreviewloops-14",
  "source_kind": "review_finding",
  "source_path": "evidence/section_14_evidence_package.json",
  "source_refs": [
    "paper:paper-8402e4affac7"
  ],
  "source_span": "Conclusions and Relevance In this study, long-term aDBS was tolerable, effective, and safe in people with PD who were previously stable while receiving cDBS.",
  "study_system": "Long-Term Personalized Adaptive Deep Brain Stimulation in Parkinson Disease: A Nonrandomized Clinical Trial.",
  "evidence_refs": [
    {
      "ref": "paper:paper-8402e4affac7"
    }
  ],
  "section_title": "Loop Dysfunction in Neurological and Psychiatric Disease",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
  },
  "evidence_summary": " (, 2025); Bronte-Stewart HM, Beudel M, Ostrem JL, Little S, Almeida L, Ramirez-Zamora A, Fasano A, Hassell T, Mitchell KT, Moro E, Gostkowski M, Chattree G, de Bie RMA, de Neeling M, Piña-Fuentes D, Swinnen B, ",
  "review_bundle_ref": "analysis_bundle:ab-d49e54403ef9",
  "replication_status": "replication_unknown",
  "review_package_ref": "analysis_bundle:ab-d49e54403ef9",
  "source_artifact_ref": "wiki_page:computationalreviewloops-14",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_14_evidence_package.json",
  "commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}