Version history

{
  "scope": "mouse S1 cortex, P3/P9/P15/P30+",
  "claim_text": "VIP-INs acquire passive membrane properties characteristic of accelerated signal integration during the second postnatal week: resting Em, input resistance Rm, capacitance Cm, and membrane time constant τ change progressively between P3, P9, P15 and P30+ in mouse S1.",
  "raw_fields": {
    "n": null,
    "doi": "10.1111/apha.14265",
    "claim": "VIP-INs acquire passive membrane properties characteristic of accelerated signal integration during the second postnatal week: resting Em, input resistance Rm, capacitance Cm, and membrane time constant τ change progressively between P3, P9, P15 and P30+ in mouse S1.",
    "title": null,
    "cite_key": "Simacek2025b",
    "evidence": "Whole-cell patch-clamp recordings in Vip-IRES-cre × tdTomato S1 cortex slices.",
    "effect_size": null,
    "figure_data": null,
    "text_access": "fulltext",
    "key_entities": [
      "VIP",
      "passive membrane properties",
      "postnatal",
      "P3",
      "P15",
      "critical period",
      "membrane time constant"
    ],
    "study_system": "mouse S1 cortex, P3/P9/P15/P30+",
    "_source_cluster": "cluster_02_development_lineage",
    "replication_status": "single_study",
    "_source_cluster_index": 122,
    "claim_source_sentence": "Statistical graphs showing developmental changes in and resting membrane potentials (Em, A), plasma membrane resistances (Rm, B), plasma membrane capacitance (Cm, C), and membrane time constant (τ, D) in VIP-INs at P3, P9, P15, and P30+ in VIP-INs.",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": null
  },
  "section_id": "section_03",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_03_evidence_package.json",
  "effect_size": null,
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-03-development",
  "source_kind": "review_finding",
  "source_path": "evidence/section_03_evidence_package.json",
  "source_refs": [
    "paper:paper-b709c20d2cb8"
  ],
  "source_span": "Statistical graphs showing developmental changes in and resting membrane potentials (Em, A), plasma membrane resistances (Rm, B), plasma membrane capacitance (Cm, C), and membrane time constant (τ, D) in VIP-INs at P3, P9, P15, and P30+ in VIP-INs.",
  "study_system": "mouse S1 cortex, P3/P9/P15/P30+",
  "evidence_refs": [
    {
      "ref": "paper:paper-b709c20d2cb8"
    }
  ],
  "section_title": "Developmental Origins and Postnatal Maturation",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "Whole-cell patch-clamp recordings in Vip-IRES-cre × tdTomato S1 cortex slices.",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "single_study",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-03-development",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_03_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}