VIP-INs acquire passive membrane properties characteristic of accelerated signa…

Details

scope: mouse S1 cortex, P3/P9/P15/P30+
section_id: section_03
source_url: https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_03_evidence_package.json
review_repo: ComputationalReviewVIP
section_ref: wiki_page:computationalreviewvip-03-development
source_kind: review_finding
source_path: evidence/section_03_evidence_package.json
study_system: mouse S1 cortex, P3/P9/P15/P30+
section_title: Developmental Origins and Postnatal Maturation
evidence_summary: Whole-cell patch-clamp recordings in Vip-IRES-cre × tdTomato S1 cortex slices.
review_bundle_ref: analysis_bundle:ab-2ce40c33e827
replication_status: single_study
review_package_ref: analysis_bundle:ab-2ce40c33e827
source_artifact_ref: wiki_page:computationalreviewvip-03-development
origin_url: https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_03_evidence_package.json
commit_sha: 95e761177f7d2ec565983d3307c14ec238f9677c
created_by: persona-jerome-lecoq-gbo-neuroscience
repository_url: https://github.com/AllenNeuralDynamics/ComputationalReviewVIP

Raw fields (6)

claim_text

VIP-INs acquire passive membrane properties characteristic of accelerated signal integration during the second postnatal week: resting Em, input resistance Rm, capacitance Cm, and membrane time constant τ change progressively between P3, P9, P15 and P30+ in mouse S1.

raw_fields

{
  "n": null,
  "doi": "10.1111/apha.14265",
  "claim": "VIP-INs acquire passive membrane properties characteristic of accelerated signal integration during the second postnatal week: resting Em, input resistance Rm, capacitance Cm, and membrane time constant τ change progressively between P3, P9, P15 and P30+ in mouse S1.",
  "title": null,
  "cite_key": "Simacek2025b",
  "evidence": "Whole-cell patch-clamp recordings in Vip-IRES-cre × tdTomato S1 cortex slices.",
  "effect_size": null,
  "figure_data": null,
  "text_access": "fulltext",
  "key_entities": [
    "VIP",
    "passive membrane properties",
    "postnatal",
    "P3",
    "P15",
    "critical period",
    "membrane time constant"
  ],
  "study_system": "mouse S1 cortex, P3/P9/P15/P30+",
  "_source_cluster": "cluster_02_development_lineage",
  "replication_status": "single_study",
  "_source_cluster_index": 122,
  "claim_source_sentence": "Statistical graphs showing developmental changes in and resting membrane potentials (Em, A), plasma membrane resistances (Rm, B), plasma membrane capacitance (Cm, C), and membrane time constant (τ, D) in VIP-INs at P3, P9, P15, and P30+ in VIP-INs.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}

source_refs

[
  "paper:paper-b709c20d2cb8"
]

source_span

Statistical graphs showing developmental changes in and resting membrane potentials (Em, A), plasma membrane resistances (Rm, B), plasma membrane capacitance (Cm, C), and membrane time constant (τ, D) in VIP-INs at P3, P9, P15, and P30+ in VIP-INs.

evidence_refs

[
  {
    "ref": "paper:paper-b709c20d2cb8"
  }
]

source_policy

{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

VIP-INs acquire passive membrane properties characteristic of accelerated signa…

Details

Replication

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