Details
- scope
- mouse whole brain (qBrain)
- section_id
- section_06
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_06_evidence_package.json
- effect_size
- >95% Cre/marker colocalization in adult isocortex; sex-dimorphic SST+/VIP+ cell numbers in 9 brain areas.
- review_repo
- ComputationalReviewVIP
- section_ref
- wiki_page:computationalreviewvip-06-synaptic-properties
- source_kind
- review_finding
- source_path
- evidence/section_06_evidence_package.json
- source_span
- Long-range feedforward inputs strongly target PV+ neurons, while long-range feedback inputs tend to target VIP+ neurons, which in turn inhibit SST+ neurons ( ; ; ).
- study_system
- mouse whole brain (qBrain)
- section_title
- Synaptic Properties and Connectivity
- evidence_summary
- Whole-brain serial two-photon tomography of Cre-driver/H2B-GFP intersectional reporters; sex-specific quantitative comparisons.
- review_bundle_ref
- analysis_bundle:ab-2ce40c33e827
- replication_status
- single-study
- review_package_ref
- analysis_bundle:ab-2ce40c33e827
- source_artifact_ref
- wiki_page:computationalreviewvip-06-synaptic-properties
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_06_evidence_package.json
- commit_sha
- 95e761177f7d2ec565983d3307c14ec238f9677c
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (5)
- claim_text
Brain-wide qBrain quantitative cell-type mapping reveals stereotyped, sex-dimorphic distributions of PV+, SST+ and VIP+ interneurons; long-range feedforward cortical inputs preferentially target PV+ cells while feedback inputs preferentially target VIP+ cells, supporting cell-type-specific circuit modules.
- raw_fields
{ "n": null, "doi": "10.1016/j.cell.2017.09.020", "claim": "Brain-wide qBrain quantitative cell-type mapping reveals stereotyped, sex-dimorphic distributions of PV+, SST+ and VIP+ interneurons; long-range feedforward cortical inputs preferentially target PV+ cells while feedback inputs preferentially target VIP+ cells, supporting cell-type-specific circuit modules.", "title": null, "cite_key": "Kim2017", "evidence": "Whole-brain serial two-photon tomography of Cre-driver/H2B-GFP intersectional reporters; sex-specific quantitative comparisons.", "effect_size": ">95% Cre/marker colocalization in adult isocortex; sex-dimorphic SST+/VIP+ cell numbers in 9 brain areas.", "text_access": "fulltext", "study_system": "mouse whole brain (qBrain)", "_source_cluster": "cluster_05_synaptic_connectivity", "replication_status": "single-study", "_source_cluster_index": 18, "claim_source_sentence": "Long-range feedforward inputs strongly target PV+ neurons, while long-range feedback inputs tend to target VIP+ neurons, which in turn inhibit SST+ neurons ( ; ; ).", "replication_evidence_dois": [], "effect_size_source_sentence": "This does not seem to be the case in the adult isocortex, where the Cre-driven labeling of the PV+, SST+, and VIP+ cells colocalizes in >95% cells with the expression of the respective reporter proteins ( ; ; )." }- source_refs
[ "paper:paper-fd3c7b95b8f7" ]
- evidence_refs
[ { "ref": "paper:paper-fd3c7b95b8f7" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }