Version history

{
  "scope": "Adult mouse V1, single-cell RNA-seq",
  "claim_text": "Single-cell RNA sequencing of adult mouse V1 yielded 49 transcriptomic cell types (23 GABAergic, 19 glutamatergic, 7 non-neuronal), some with specific axonal-projection and electrophysiological signatures — the foundational E→E cell-type taxonomy that mouse-cortex synthesis still anchors to.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1038/nn.4216",
    "claim": "Single-cell RNA sequencing of adult mouse V1 yielded 49 transcriptomic cell types (23 GABAergic, 19 glutamatergic, 7 non-neuronal), some with specific axonal-projection and electrophysiological signatures — the foundational E→E cell-type taxonomy that mouse-cortex synthesis still anchors to.",
    "cite_key": "Tasic2016",
    "evidence": "49 V1 transcriptomic cell types; subset matched to Cre-line genetic access, axon projection, and electrophysiology.",
    "effect_size": "49 transcriptomic cell types (19 glutamatergic) in adult mouse V1",
    "text_access": "abstract_only",
    "study_system": "Adult mouse V1, single-cell RNA-seq",
    "argument_role": "supporting",
    "replication_status": "superseded-by-2018-extended",
    "claim_source_sentence": "We constructed a cellular taxonomy of one cortical region, primary visual cortex, in adult mice on the basis of single-cell RNA sequencing. We identified 49 transcriptomic cell types, including 23 GABAergic, 19 glutamatergic and 7 non-neuronal types.",
    "source_provenance_status": "non_substring_match",
    "replication_evidence_dois": [
      "10.1038/s41586-018-0654-5"
    ],
    "effect_size_source_sentence": "We identified 49 transcriptomic cell types, including 23 GABAergic, 19 glutamatergic and 7 non-neuronal types."
  },
  "section_id": "section_15",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_15_evidence_package.json",
  "effect_size": "49 transcriptomic cell types (19 glutamatergic) in adult mouse V1",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-15-methods-limits",
  "source_kind": "review_finding",
  "source_path": "evidence/section_15_evidence_package.json",
  "source_refs": [
    "paper:paper-ed2a7f08ef35"
  ],
  "source_span": "We constructed a cellular taxonomy of one cortical region, primary visual cortex, in adult mice on the basis of single-cell RNA sequencing. We identified 49 transcriptomic cell types, including 23 GABAergic, 19 glutamatergic and 7 non-neuronal types.",
  "study_system": "Adult mouse V1, single-cell RNA-seq",
  "evidence_refs": [
    {
      "ref": "paper:paper-ed2a7f08ef35"
    }
  ],
  "section_title": "15. Methodological limits and emerging tools — what current mouse-cortex tools cannot yet measure about E→E recurrence (subthreshold network activity, fast plasticity in vivo, millimetre-scale dynamic connectomes), and what is on the near horizon",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "49 V1 transcriptomic cell types; subset matched to Cre-line genetic access, axon projection, and electrophysiology.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "superseded-by-2018-extended",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-15-methods-limits",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_15_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}