- claim_text
Single-cell RNA sequencing of adult mouse V1 yielded 49 transcriptomic cell types (23 GABAergic, 19 glutamatergic, 7 non-neuronal), some with specific axonal-projection and electrophysiological signatures — the foundational E→E cell-type taxonomy that mouse-cortex synthesis still anchors to.
- raw_fields
{
"n": 0,
"doi": "10.1038/nn.4216",
"claim": "Single-cell RNA sequencing of adult mouse V1 yielded 49 transcriptomic cell types (23 GABAergic, 19 glutamatergic, 7 non-neuronal), some with specific axonal-projection and electrophysiological signatures — the foundational E→E cell-type taxonomy that mouse-cortex synthesis still anchors to.",
"cite_key": "Tasic2016",
"evidence": "49 V1 transcriptomic cell types; subset matched to Cre-line genetic access, axon projection, and electrophysiology.",
"effect_size": "49 transcriptomic cell types (19 glutamatergic) in adult mouse V1",
"text_access": "abstract_only",
"study_system": "Adult mouse V1, single-cell RNA-seq",
"argument_role": "supporting",
"replication_status": "superseded-by-2018-extended",
"claim_source_sentence": "We constructed a cellular taxonomy of one cortical region, primary visual cortex, in adult mice on the basis of single-cell RNA sequencing. We identified 49 transcriptomic cell types, including 23 GABAergic, 19 glutamatergic and 7 non-neuronal types.",
"source_provenance_status": "non_substring_match",
"replication_evidence_dois": [
"10.1038/s41586-018-0654-5"
],
"effect_size_source_sentence": "We identified 49 transcriptomic cell types, including 23 GABAergic, 19 glutamatergic and 7 non-neuronal types."
}- source_refs
[
"paper:paper-ed2a7f08ef35"
]
- source_span
We constructed a cellular taxonomy of one cortical region, primary visual cortex, in adult mice on the basis of single-cell RNA sequencing. We identified 49 transcriptomic cell types, including 23 GABAergic, 19 glutamatergic and 7 non-neuronal types.
- evidence_refs
[
{
"ref": "paper:paper-ed2a7f08ef35"
}
]- section_title
15. Methodological limits and emerging tools — what current mouse-cortex tools cannot yet measure about E→E recurrence (subthreshold network activity, fast plasticity in vivo, millimetre-scale dynamic connectomes), and what is on the near horizon
- source_policy
{
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"notes": [
"Local review repositories are read-only inputs.",
"SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
],
"source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
"source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}