Version history

{
  "scope": "mouse (single-neuron Sindbis labeling + serial reconstruction)",
  "claim_text": "Single-cell axon reconstruction of mouse ventral tegmental area neurons reveals two morphological classes — forebrain-projecting (FPN) and forebrain+brainstem-projecting (F+BSPN) — and four subtypes among FPNs based on projection target, including a mesostriatal subtype targeting only the caudate-putamen.",
  "raw_fields": {
    "n": 30,
    "doi": "10.3389/fnana.2015.00059",
    "claim": "Single-cell axon reconstruction of mouse ventral tegmental area neurons reveals two morphological classes — forebrain-projecting (FPN) and forebrain+brainstem-projecting (F+BSPN) — and four subtypes among FPNs based on projection target, including a mesostriatal subtype targeting only the caudate-putamen.",
    "cite_key": "Aransay2015",
    "evidence": "Single-cell Sindbis-pal-eGFP transfection of VTA neurons (n=30) with serial-section axon reconstruction and stereological measurement.",
    "effect_size": "30 single VTA neurons reconstructed; 4 FPN subtypes (mesocorticolimbic, mesocortical, mesolimbic, mesostriatal)",
    "text_access": "abstract_only",
    "study_system": "mouse (single-neuron Sindbis labeling + serial reconstruction)",
    "source_cluster_id": "cluster_03",
    "replication_status": "replication_unknown",
    "claim_source_sentence": "We observed two main, markedly different VTA cell morphologies: neurons with a single main axon targeting only forebrain structures (FPN cells), and neurons with multibranched axons targeting both the forebrain and the brainstem (F + BSPN cells).",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "(4) \"Mesostriatal\" FPN targeting only the caudateputamen."
  },
  "section_id": "section_03",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_03_evidence_package.json",
  "effect_size": "30 single VTA neurons reconstructed; 4 FPN subtypes (mesocorticolimbic, mesocortical, mesolimbic, mesostriatal)",
  "review_repo": "ComputationalReviewLoops",
  "section_ref": "wiki_page:computationalreviewloops-03",
  "source_kind": "review_finding",
  "source_path": "evidence/section_03_evidence_package.json",
  "source_refs": [
    "paper:paper-353c1a63d3ff"
  ],
  "source_span": "We observed two main, markedly different VTA cell morphologies: neurons with a single main axon targeting only forebrain structures (FPN cells), and neurons with multibranched axons targeting both the forebrain and the brainstem (F + BSPN cells).",
  "study_system": "mouse (single-neuron Sindbis labeling + serial reconstruction)",
  "evidence_refs": [
    {
      "ref": "paper:paper-353c1a63d3ff"
    }
  ],
  "section_title": "The Cortico-Striatal Interface: Topography, Cell Types, and Input Convergence",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
  },
  "evidence_summary": "Single-cell Sindbis-pal-eGFP transfection of VTA neurons (n=30) with serial-section axon reconstruction and stereological measurement.",
  "review_bundle_ref": "analysis_bundle:ab-d49e54403ef9",
  "replication_status": "replication_unknown",
  "review_package_ref": "analysis_bundle:ab-d49e54403ef9",
  "source_artifact_ref": "wiki_page:computationalreviewloops-03",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_03_evidence_package.json",
  "commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}