Version history

{
  "scope": "mouse barrel cortex slice, layers IV–V",
  "claim_text": "Thalamocortical input to mouse barrel cortex evokes action potentials in ~60% of inhibitory interneurons but in <5% of excitatory neurons, with the firing inhibitory interneurons receiving roughly fivefold larger thalamocortical EPSCs — establishing inhibitory cells as the dominant disynaptic feedforward inhibitor.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1523/jneurosci.21-08-02699.2001",
    "claim": "Thalamocortical input to mouse barrel cortex evokes action potentials in ~60% of inhibitory interneurons but in <5% of excitatory neurons, with the firing inhibitory interneurons receiving roughly fivefold larger thalamocortical EPSCs — establishing inhibitory cells as the dominant disynaptic feedforward inhibitor.",
    "cite_key": "Porter2001",
    "evidence": "Cell-attached and whole-cell recordings in layer-IV/V mouse barrel cortex slice with thalamocortical stimulation.",
    "effect_size": "5-fold larger TC inputs onto firing inhibitory interneurons; 60% vs <5% spike probability for inhibitory vs excitatory cells",
    "text_access": "abstract_only",
    "study_system": "mouse barrel cortex slice, layers IV–V",
    "source_cluster_id": "cluster_05",
    "replication_status": "independently_replicated",
    "claim_source_sentence": "Thalamocortical stimulation evoked action potentials in approximately 60% of inhibitory interneurons but in <5% of excitatory neurons.",
    "replication_evidence_dois": [
      "10.1152/jn.00549.2001",
      "10.1093/cercor/4.6.646"
    ],
    "effect_size_source_sentence": "The inhibitory interneurons that fired received fivefold larger thalamocortical inputs compared with nonfiring inhibitory or excitatory neurons."
  },
  "section_id": "section_06",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_06_evidence_package.json",
  "effect_size": "5-fold larger TC inputs onto firing inhibitory interneurons; 60% vs <5% spike probability for inhibitory vs excitatory cells",
  "review_repo": "ComputationalReviewLoops",
  "section_ref": "wiki_page:computationalreviewloops-06",
  "source_kind": "review_finding",
  "source_path": "evidence/section_06_evidence_package.json",
  "source_refs": [
    "paper:paper-3eb6456daece"
  ],
  "source_span": "Thalamocortical stimulation evoked action potentials in approximately 60% of inhibitory interneurons but in <5% of excitatory neurons.",
  "study_system": "mouse barrel cortex slice, layers IV–V",
  "evidence_refs": [
    {
      "ref": "paper:paper-3eb6456daece"
    }
  ],
  "section_title": "Thalamic Feedback: Closing the Loop",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
  },
  "evidence_summary": "Cell-attached and whole-cell recordings in layer-IV/V mouse barrel cortex slice with thalamocortical stimulation.",
  "review_bundle_ref": "analysis_bundle:ab-d49e54403ef9",
  "replication_status": "independently_replicated",
  "review_package_ref": "analysis_bundle:ab-d49e54403ef9",
  "source_artifact_ref": "wiki_page:computationalreviewloops-06",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_06_evidence_package.json",
  "commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}