Version history

{
  "scope": "mouse V1, VIP-Cre × Ai14 with HTR3A-GFP, PV-Cre, Sst-Cre crosses",
  "claim_text": "VIP-Cre cell population is entirely contained within the HTR3A-GFP population (100% overlap of VIP-Cre/tdTomato with HTR3A-GFP) and shows zero overlap with PV-Cre or Sst-Cre populations, validating VIP-Cre as a clean genetic handle that selects a subset of the broader 5HT3aR class.",
  "raw_fields": {
    "n": null,
    "doi": "10.1038/nn.3446",
    "claim": "VIP-Cre cell population is entirely contained within the HTR3A-GFP population (100% overlap of VIP-Cre/tdTomato with HTR3A-GFP) and shows zero overlap with PV-Cre or Sst-Cre populations, validating VIP-Cre as a clean genetic handle that selects a subset of the broader 5HT3aR class.",
    "title": null,
    "cite_key": "Pfeffer2013",
    "evidence": "VIP-Cre×Ai14 cross with HTR3A-GFP reporter mice; quantitative co-localization across L2/3 and L5",
    "effect_size": "VIP-Cre overlap: HTR3A-GFP 100%; PV-Cre 0%; Sst-Cre 0%",
    "text_access": "fulltext",
    "study_system": "mouse V1, VIP-Cre × Ai14 with HTR3A-GFP, PV-Cre, Sst-Cre crosses",
    "_source_cluster": "cluster_04_intrinsic_electrophysiology",
    "replication_status": "replicated",
    "_source_cluster_index": 37,
    "claim_source_sentence": "Virtually all VIP-Cre cells (visualized by tdTomato expression) also expressed green fluorescent protein (GFP) (100%; Fig.",
    "replication_evidence_dois": [
      "10.1523/jneurosci.1869-10.2010"
    ],
    "effect_size_source_sentence": "Thus, the VIP-Cre population is a sub-population of and is entirely comprised in the HTR3A-GFP population."
  },
  "section_id": "section_05",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json",
  "effect_size": "VIP-Cre overlap: HTR3A-GFP 100%; PV-Cre 0%; Sst-Cre 0%",
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-05-electrophysiology",
  "source_kind": "review_finding",
  "source_path": "evidence/section_05_evidence_package.json",
  "source_refs": [
    "paper:paper-1659c2dc5d60"
  ],
  "source_span": "Virtually all VIP-Cre cells (visualized by tdTomato expression) also expressed green fluorescent protein (GFP) (100%; Fig.",
  "study_system": "mouse V1, VIP-Cre × Ai14 with HTR3A-GFP, PV-Cre, Sst-Cre crosses",
  "evidence_refs": [
    {
      "ref": "paper:paper-1659c2dc5d60"
    }
  ],
  "section_title": "Intrinsic Electrophysiology",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "VIP-Cre×Ai14 cross with HTR3A-GFP reporter mice; quantitative co-localization across L2/3 and L5",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "replicated",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-05-electrophysiology",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_05_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}