Version history

{
  "scope": "mouse neocortex slice (5-HT3A:GFP)",
  "claim_text": "5-HT3A receptor expression demarcates two electrophysiologically distinct subclasses of cortical CGE-derived interneurons: a VIP-expressing bipolar/bitufted cluster (n=22) and an NPY-expressing cluster (n=31) with more complex dendrites; ~73% of VIP-cluster cells co-express VIP mRNA, forming the principal molecular framework for 5HT3aR+ inhibition.",
  "raw_fields": {
    "n": 53,
    "doi": "10.1093/cercor/bhp310",
    "claim": "5-HT3A receptor expression demarcates two electrophysiologically distinct subclasses of cortical CGE-derived interneurons: a VIP-expressing bipolar/bitufted cluster (n=22) and an NPY-expressing cluster (n=31) with more complex dendrites; ~73% of VIP-cluster cells co-express VIP mRNA, forming the principal molecular framework for 5HT3aR+ inhibition.",
    "title": null,
    "cite_key": "Vucurovic2010",
    "evidence": "Whole-cell patch-clamp + scRT-PCR + GFP transgenic 5HT3a:GFP mice; unsupervised clustering on 53 cells.",
    "effect_size": "VIP cluster n=22, NPY cluster n=31; 16/22 (73%) VIP-cluster cells express VIP mRNA",
    "text_access": "fulltext",
    "study_system": "mouse neocortex slice (5-HT3A:GFP)",
    "_source_cluster": "cluster_05_synaptic_connectivity",
    "replication_status": "replicated",
    "_source_cluster_index": 19,
    "claim_source_sentence": "The VIP-cluster of 5-HT 3A Interneurons Unsupervised clustering discriminated another group of cells characterized by a high occurrence of VIP mRNA ( n = 16/22, 73%).",
    "replication_evidence_dois": [
      "10.1523/jneurosci.22-17-07389.2002"
    ],
    "effect_size_source_sentence": "Unsupervised clustering discriminated another group of cells characterized by a high occurrence of VIP mRNA ( n = 16/22, 73%)."
  },
  "section_id": "section_06",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_06_evidence_package.json",
  "effect_size": "VIP cluster n=22, NPY cluster n=31; 16/22 (73%) VIP-cluster cells express VIP mRNA",
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-06-synaptic-properties",
  "source_kind": "review_finding",
  "source_path": "evidence/section_06_evidence_package.json",
  "source_refs": [
    "paper:paper-0336a131683f"
  ],
  "source_span": "The VIP-cluster of 5-HT 3A Interneurons Unsupervised clustering discriminated another group of cells characterized by a high occurrence of VIP mRNA ( n = 16/22, 73%).",
  "study_system": "mouse neocortex slice (5-HT3A:GFP)",
  "evidence_refs": [
    {
      "ref": "paper:paper-0336a131683f"
    }
  ],
  "section_title": "Synaptic Properties and Connectivity",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "Whole-cell patch-clamp + scRT-PCR + GFP transgenic 5HT3a:GFP mice; unsupervised clustering on 53 cells.",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "replicated",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-06-synaptic-properties",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_06_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}