Details

scope
mouse V1
section_id
section_01
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_01_evidence_package.json
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-01-introduction
source_kind
review_finding
source_path
evidence/section_01_evidence_package.json
study_system
mouse V1
section_title
Introduction
evidence_summary
Inhibitory stabilization and visual coding in cortical circuits with multiple interneuron subtypes
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
replication_unknown
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-01-introduction
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_01_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (6)
claim_text
We study the dynamics of recurrent excitatory-inhibitory model cortical networks with parvalbumin (PV)-, somatostatin (SOM)-, and vasointestinal peptide-expressing (VIP) interneurons, with connectivity properties motivated by experimental recordings from mouse primary visual cortex.
raw_fields
{
  "n": null,
  "doi": "10.1152/jn.00732.2015",
  "year": "2016",
  "claim": "We study the dynamics of recurrent excitatory-inhibitory model cortical networks with parvalbumin (PV)-, somatostatin (SOM)-, and vasointestinal peptide-expressing (VIP) interneurons, with connectivity properties motivated by experimental recordings from mouse primary visual cortex.",
  "title": null,
  "journal": "Journal of neurophysiology",
  "cite_key": "Litwinkumar2016",
  "evidence": "Inhibitory stabilization and visual coding in cortical circuits with multiple interneuron subtypes",
  "effect_size": null,
  "text_access": "abstract_only",
  "first_author": "Litwin-Kumar",
  "study_system": "mouse V1",
  "_source_cluster": "cluster_06_disinhibition_circuit",
  "author_list_short": "Litwin-Kumar, Rosenbaum, Doiron",
  "replication_status": "replication_unknown",
  "_collapsed_provenance": [
    {
      "doi": "10.1152/jn.00732.2015",
      "claim": "A recurrent excitatory-inhibitory model with PV, SST and VIP interneurons (connectivity from mouse V1 recordings) shows that disinhibition, surround suppression, and subtractive vs divisive gain modulation of orientation tuning each impose distinct architectural and stimulus-tuning constraints — recurrent inhibitory dynamics must be modeled with multiple IN classes to reproduce experimental cortical phenomena.",
      "source_cluster": "cluster_01_molecular_taxonomy",
      "source_cluster_index": 73
    }
  ],
  "_source_cluster_index": 28,
  "claim_source_sentence": "We study the dynamics of recurrent excitatory-inhibitory model cortical networks with parvalbumin (PV)-, somatostatin (SOM)-, and vasointestinal peptide-expressing (VIP) interneurons, with connectivity properties motivated by experimental recordings from mouse primary visual cortex.",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-8f25714ab7fe"
]
source_span
We study the dynamics of recurrent excitatory-inhibitory model cortical networks with parvalbumin (PV)-, somatostatin (SOM)-, and vasointestinal peptide-expressing (VIP) interneurons, with connectivity properties motivated by experimental recordings from mouse primary visual cortex.
evidence_refs
[
  {
    "ref": "paper:paper-8f25714ab7fe"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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