Version history
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- Live5/17/2026, 4:35:28 PM
5a90e79dc9d0Content snapshot
{ "scope": "mouse cerebral cortex, review of neuroanatomical tracing and neurophysiology", "claim_text": "Layer 2/3 cortical pyramidal neurons distribute axons principally within the cerebral cortex, while layer 5 pyramidal tract neurons project ipsilaterally within the cortex and to subcortical targets, and layer 5 inter-telencephalic neurons project bilaterally to the cerebral cortex and striatum.", "raw_fields": { "n": 0, "doi": "10.1002/jnr.23978", "claim": "Layer 2/3 cortical pyramidal neurons distribute axons principally within the cerebral cortex, while layer 5 pyramidal tract neurons project ipsilaterally within the cortex and to subcortical targets, and layer 5 inter-telencephalic neurons project bilaterally to the cerebral cortex and striatum.", "cite_key": "Gerfen2018", "evidence": "Review of neuroanatomical tracing studies using GENSAT BAC-Cre transgenic mouse lines combined with AAV-GFP anterograde tracing and rabies virus retrograde tracing to characterize long-distance projections of cortical pyramidal neuron subtypes.", "effect_size": "", "text_access": "fulltext", "study_system": "mouse cerebral cortex, review of neuroanatomical tracing and neurophysiology", "argument_role": "supporting", "replication_status": "consistent_with_prior", "claim_source_sentence": "As described above, cortical pyramidal neurons in layers 2 and 3 give rise to axonal projections distributed within the cerebral cortex, while layer 5 is composed of two main subtypes, inter-telencephalic neurons (IT) providing projections bilaterally to the cerebral cortex and striatum, and pyramidal tract neurons (PT) that provide inputs ipsilaterally to the cortex and subcortical structures.", "source_provenance_status": "ok", "replication_evidence_dois": [], "effect_size_source_sentence": "" }, "section_id": "section_05", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_05_evidence_package.json", "effect_size": "", "review_repo": "ComputationalReviewRecurrence", "section_ref": "wiki_page:computationalreviewrecurrence-05-horizontal", "source_kind": "review_finding", "source_path": "evidence/section_05_evidence_package.json", "source_refs": [ "paper:paper-b0b284f0f8b1" ], "source_span": "As described above, cortical pyramidal neurons in layers 2 and 3 give rise to axonal projections distributed within the cerebral cortex, while layer 5 is composed of two main subtypes, inter-telencephalic neurons (IT) providing projections bilaterally to the cerebral cortex and striatum, and pyramidal tract neurons (PT) that provide inputs ipsilaterally to the cortex and subcortical structures.", "study_system": "mouse cerebral cortex, review of neuroanatomical tracing and neurophysiology", "evidence_refs": [ { "ref": "paper:paper-b0b284f0f8b1" } ], "section_title": "5. Horizontal long-range intracortical excitatory connections in mouse — patchy L2/3-L5 axons, similarity tuning, distance-decay", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }, "evidence_summary": "Review of neuroanatomical tracing studies using GENSAT BAC-Cre transgenic mouse lines combined with AAV-GFP anterograde tracing and rabies virus retrograde tracing to characterize long-distance projections of cortical pyramidal neuron subtypes.", "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9", "replication_status": "consistent_with_prior", "review_package_ref": "analysis_bundle:ab-d9c479db9be9", "source_artifact_ref": "wiki_page:computationalreviewrecurrence-05-horizontal", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_05_evidence_package.json", "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }