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- Live5/17/2026, 4:35:28 PM
8c83083acae4Content snapshot
{ "scope": "mouse hippocampal PV interneurons", "claim_text": "PV interneurons show high transcriptomic similarity across morphologically distinct subtypes, with continuous rather than discrete transcriptomic landscapes.", "raw_fields": { "n": 0, "doi": "10.1038/s41467-020-20328-4", "claim": "PV interneurons show high transcriptomic similarity across morphologically distinct subtypes, with continuous rather than discrete transcriptomic landscapes.", "evidence": "Single-cell RNA-seq in morphologically identified PV interneurons in hippocampus showed uniform transcriptomic and biophysical profiles despite anatomical differences.", "effect_size": "few genes divergent between morphological types; uniform CAM profile", "text_access": "fulltext", "study_system": "mouse hippocampal PV interneurons", "replication_status": "replication_unknown", "claim_source_sentence": "Overall, we find high transcriptomic similarity among PV-INs, with few genes showing divergent expression between morphologically different types.", "replication_evidence_dois": [], "effect_size_source_sentence": "PV-INs show a uniform synaptic cell adhesion molecule (CAM) profile, suggesting that CAM expression in mature PV cells does not reflect wiring specificity after development." }, "section_id": "section_02_evidence_package", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_02_evidence_package.json", "effect_size": "few genes divergent between morphological types; uniform CAM profile", "review_repo": "ComputationalReviewPV", "section_ref": "wiki_page:computationalreviewpv-02", "source_kind": "review_finding", "source_path": "evidence/section_02_evidence_package.json", "source_refs": [ "paper:paper-81b583f41ed6" ], "source_span": "Overall, we find high transcriptomic similarity among PV-INs, with few genes showing divergent expression between morphologically different types.", "study_system": "mouse hippocampal PV interneurons", "evidence_refs": [ { "ref": "paper:paper-81b583f41ed6" } ], "section_title": "Molecular Identity and Transcriptomic Taxonomy", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }, "evidence_summary": "Single-cell RNA-seq in morphologically identified PV interneurons in hippocampus showed uniform transcriptomic and biophysical profiles despite anatomical differences.", "review_bundle_ref": "analysis_bundle:ab-e6261c8263e7", "replication_status": "replication_unknown", "review_package_ref": "analysis_bundle:ab-e6261c8263e7", "source_artifact_ref": "wiki_page:computationalreviewpv-02", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_02_evidence_package.json", "commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV" }