Details
- scope
- 6-OHDA-lesioned rats, multi-site GPe and STN recording
- claim_text
- In a 6-OHDA rat model, GPe neurons become coherent with STN at parkinsonian beta frequencies; synchronization increases ~100-fold while mean firing rate decreases — refining a rate-only view of basal ganglia dysfunction.
- section_id
- section_05
- source_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_05_evidence_package.json
- effect_size
- ~100-fold increase in synchronization; mean firing rate decreased relative to controls
- review_repo
- ComputationalReviewLoops
- section_ref
- wiki_page:computationalreviewloops-05
- source_kind
- review_finding
- source_path
- evidence/section_05_evidence_package.json
- source_span
- Although synchronization of GP unit activity increased by almost 100-fold during beta oscillations, the mean firing rate of GP neurons decreased compared with controls.
- study_system
- 6-OHDA-lesioned rats, multi-site GPe and STN recording
- section_title
- Pallidal Organization and the Disinhibition Principle
- evidence_summary
- review_bundle_ref
- analysis_bundle:ab-d49e54403ef9
- replication_status
- replicated
- review_package_ref
- analysis_bundle:ab-d49e54403ef9
- source_artifact_ref
- wiki_page:computationalreviewloops-05
- origin_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_05_evidence_package.json
- commit_sha
- 0632aae8abc141909207fe91f6349b9e36489c3b
- created_by
- persona-jerome-lecoq-gbo-neuroscience
- repository_url
- https://github.com/AllenNeuralDynamics/ComputationalReviewLoops
Raw fields (4)
- raw_fields
{ "n": 0, "doi": "10.1523/jneurosci.4199-08.2008", "claim": "In a 6-OHDA rat model, GPe neurons become coherent with STN at parkinsonian beta frequencies; synchronization increases ~100-fold while mean firing rate decreases — refining a rate-only view of basal ganglia dysfunction.", "cite_key": "Mallet2008", "evidence": "", "effect_size": "~100-fold increase in synchronization; mean firing rate decreased relative to controls", "text_access": "abstract_only", "study_system": "6-OHDA-lesioned rats, multi-site GPe and STN recording", "source_cluster_id": "cluster_04", "replication_status": "replicated", "claim_source_sentence": "Although synchronization of GP unit activity increased by almost 100-fold during beta oscillations, the mean firing rate of GP neurons decreased compared with controls.", "replication_evidence_dois": [ "10.1523/jneurosci.21-03-01033.2001" ], "effect_size_source_sentence": "Although synchronization of GP unit activity increased by almost 100-fold during beta oscillations, the mean firing rate of GP neurons decreased compared with controls." }- source_refs
[ "paper:paper-84f5af1f970c" ]
- evidence_refs
[ { "ref": "paper:paper-84f5af1f970c" } ]- source_policy
{ "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops" }