Version history

{
  "scope": "6-OHDA-lesioned rats, multi-site GPe and STN recording",
  "claim_text": "In a 6-OHDA rat model, GPe neurons become coherent with STN at parkinsonian beta frequencies; synchronization increases ~100-fold while mean firing rate decreases — refining a rate-only view of basal ganglia dysfunction.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1523/jneurosci.4199-08.2008",
    "claim": "In a 6-OHDA rat model, GPe neurons become coherent with STN at parkinsonian beta frequencies; synchronization increases ~100-fold while mean firing rate decreases — refining a rate-only view of basal ganglia dysfunction.",
    "cite_key": "Mallet2008",
    "evidence": "",
    "effect_size": "~100-fold increase in synchronization; mean firing rate decreased relative to controls",
    "text_access": "abstract_only",
    "study_system": "6-OHDA-lesioned rats, multi-site GPe and STN recording",
    "source_cluster_id": "cluster_04",
    "replication_status": "replicated",
    "claim_source_sentence": "Although synchronization of GP unit activity increased by almost 100-fold during beta oscillations, the mean firing rate of GP neurons decreased compared with controls.",
    "replication_evidence_dois": [
      "10.1523/jneurosci.21-03-01033.2001"
    ],
    "effect_size_source_sentence": "Although synchronization of GP unit activity increased by almost 100-fold during beta oscillations, the mean firing rate of GP neurons decreased compared with controls."
  },
  "section_id": "section_05",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_05_evidence_package.json",
  "effect_size": "~100-fold increase in synchronization; mean firing rate decreased relative to controls",
  "review_repo": "ComputationalReviewLoops",
  "section_ref": "wiki_page:computationalreviewloops-05",
  "source_kind": "review_finding",
  "source_path": "evidence/section_05_evidence_package.json",
  "source_refs": [
    "paper:paper-84f5af1f970c"
  ],
  "source_span": "Although synchronization of GP unit activity increased by almost 100-fold during beta oscillations, the mean firing rate of GP neurons decreased compared with controls.",
  "study_system": "6-OHDA-lesioned rats, multi-site GPe and STN recording",
  "evidence_refs": [
    {
      "ref": "paper:paper-84f5af1f970c"
    }
  ],
  "section_title": "Pallidal Organization and the Disinhibition Principle",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
  },
  "evidence_summary": "",
  "review_bundle_ref": "analysis_bundle:ab-d49e54403ef9",
  "replication_status": "replicated",
  "review_package_ref": "analysis_bundle:ab-d49e54403ef9",
  "source_artifact_ref": "wiki_page:computationalreviewloops-05",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_05_evidence_package.json",
  "commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}