Details

scope
Mouse visual cortex; calcium imaging and holographic optogenetics (review)
section_id
section_16
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_16_evidence_package.json
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-16-synthesis
source_kind
review_finding
source_path
evidence/section_16_evidence_package.json
source_span
Calcium imaging and optogenetics have enabled mapping and manipulating ensembles with single-cell resolution in mouse visual cortex, providing evidence of their importance.
study_system
Mouse visual cortex; calcium imaging and holographic optogenetics (review)
section_title
16. Synthesis — which computational claims the mouse-cortex E→E empirical record actually supports, where the bottleneck observations are, and what an inhibition-free, single-species, basic-research analytic framing misses
evidence_summary
Synthesis review consolidating two-photon + all-optical evidence about ensembles in mouse V1 — directly relevant to cluster_14's E→E synthesis and all-optical scope.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
single-study
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-16-synthesis
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_16_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (5)
claim_text
Calcium imaging and optogenetics with single-cell resolution in mouse visual cortex have enabled mapping and manipulation of neuronal ensembles, which can be imprinted by synchronous activation and reactivated by 'pattern completion' trigger cells, providing evidence that ensembles are physiological modules of the cerebral cortex.
raw_fields
{
  "n": 0,
  "doi": "10.1152/physrev.00003.2025",
  "claim": "Calcium imaging and optogenetics with single-cell resolution in mouse visual cortex have enabled mapping and manipulation of neuronal ensembles, which can be imprinted by synchronous activation and reactivated by 'pattern completion' trigger cells, providing evidence that ensembles are physiological modules of the cerebral cortex.",
  "cite_key": "Yuste2026",
  "evidence": "Synthesis review consolidating two-photon + all-optical evidence about ensembles in mouse V1 — directly relevant to cluster_14's E→E synthesis and all-optical scope.",
  "effect_size": null,
  "text_access": "abstract_only",
  "study_system": "Mouse visual cortex; calcium imaging and holographic optogenetics (review)",
  "argument_role": "supporting",
  "replication_status": "single-study",
  "claim_source_sentence": "Calcium imaging and optogenetics have enabled mapping and manipulating ensembles with single-cell resolution in mouse visual cortex, providing evidence of their importance.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-fb9d6c04dc50"
]
evidence_refs
[
  {
    "ref": "paper:paper-fb9d6c04dc50"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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