Version history

{
  "scope": "Mouse visual cortex; calcium imaging and holographic optogenetics (review)",
  "claim_text": "Calcium imaging and optogenetics with single-cell resolution in mouse visual cortex have enabled mapping and manipulation of neuronal ensembles, which can be imprinted by synchronous activation and reactivated by 'pattern completion' trigger cells, providing evidence that ensembles are physiological modules of the cerebral cortex.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1152/physrev.00003.2025",
    "claim": "Calcium imaging and optogenetics with single-cell resolution in mouse visual cortex have enabled mapping and manipulation of neuronal ensembles, which can be imprinted by synchronous activation and reactivated by 'pattern completion' trigger cells, providing evidence that ensembles are physiological modules of the cerebral cortex.",
    "cite_key": "Yuste2026",
    "evidence": "Synthesis review consolidating two-photon + all-optical evidence about ensembles in mouse V1 — directly relevant to cluster_14's E→E synthesis and all-optical scope.",
    "effect_size": null,
    "text_access": "abstract_only",
    "study_system": "Mouse visual cortex; calcium imaging and holographic optogenetics (review)",
    "argument_role": "supporting",
    "replication_status": "single-study",
    "claim_source_sentence": "Calcium imaging and optogenetics have enabled mapping and manipulating ensembles with single-cell resolution in mouse visual cortex, providing evidence of their importance.",
    "source_provenance_status": "non_substring_match",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": null
  },
  "section_id": "section_16",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_16_evidence_package.json",
  "effect_size": null,
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-16-synthesis",
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  "source_path": "evidence/section_16_evidence_package.json",
  "source_refs": [
    "paper:paper-fb9d6c04dc50"
  ],
  "source_span": "Calcium imaging and optogenetics have enabled mapping and manipulating ensembles with single-cell resolution in mouse visual cortex, providing evidence of their importance.",
  "study_system": "Mouse visual cortex; calcium imaging and holographic optogenetics (review)",
  "evidence_refs": [
    {
      "ref": "paper:paper-fb9d6c04dc50"
    }
  ],
  "section_title": "16. Synthesis — which computational claims the mouse-cortex E→E empirical record actually supports, where the bottleneck observations are, and what an inhibition-free, single-species, basic-research analytic framing misses",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Synthesis review consolidating two-photon + all-optical evidence about ensembles in mouse V1 — directly relevant to cluster_14's E→E synthesis and all-optical scope.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "single-study",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-16-synthesis",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_16_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}