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- Live5/17/2026, 4:35:28 PM
d865afe77223Content snapshot
{ "scope": "spiking E/I assembly learning model", "claim_text": "Recurrent spiking network with biologically realistic PV, SST and VIP populations learns excitatory-inhibitory neuronal assemblies; VIP disinhibition gates assembly recruitment.", "raw_fields": { "n": null, "id": "cluster_11_finding_63", "doi": "10.7554/elife.59715", "pmid": "33900199", "year": "2021", "claim": "Recurrent spiking network with biologically realistic PV, SST and VIP populations learns excitatory-inhibitory neuronal assemblies; VIP disinhibition gates assembly recruitment.", "pmcid": "PMC8075581", "title": "Learning excitatory-inhibitory neuronal assemblies in recurrent networks.", "authors": "Mackwood O, Naumann LB, Sprekeler H.", "journal": "eLife", "cite_key": "Mackwood2021", "evidence": "Spiking network with STDP-like rules across multiple interneuron types; quantifies how VIP gates lateral inhibition during learning.", "effect_size": null, "text_access": "fulltext", "study_system": "spiking E/I assembly learning model", "_source_cluster": "cluster_11_computational_models", "replication_status": "replicated_independent", "_source_cluster_index": 62, "claim_source_sentence": "To investigate the effect of stimulus-specific inhibition in our network, we simulate the perturbation experiment of Chettih and Harvey, 2019 : First, we again expose the network to the stimulus set, with PV input and output plasticity in place to learn E/I assemblies.", "replication_evidence_dois": [ "10.1016/j.neuron.2023.11.006", "10.1101/2025.05.13.653877", "10.1101/2024.09.30.615819", "10.1016/j.neuron.2018.03.037", "10.1162/netn_a_00427" ], "effect_size_source_sentence": null }, "section_id": "section_12", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json", "effect_size": null, "review_repo": "ComputationalReviewVIP", "section_ref": "wiki_page:computationalreviewvip-12-computational-models", "source_kind": "review_finding", "source_path": "evidence/section_12_evidence_package.json", "source_refs": [ "paper:paper-ce8a09f59a46" ], "source_span": "To investigate the effect of stimulus-specific inhibition in our network, we simulate the perturbation experiment of Chettih and Harvey, 2019 : First, we again expose the network to the stimulus set, with PV input and output plasticity in place to learn E/I assemblies.", "study_system": "spiking E/I assembly learning model", "evidence_refs": [ { "ref": "paper:paper-ce8a09f59a46" } ], "section_title": "Computational Models of VIP Circuit Function", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }, "evidence_summary": "Spiking network with STDP-like rules across multiple interneuron types; quantifies how VIP gates lateral inhibition during learning.", "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827", "replication_status": "replicated_independent", "review_package_ref": "analysis_bundle:ab-2ce40c33e827", "source_artifact_ref": "wiki_page:computationalreviewvip-12-computational-models", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json", "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP" }