Details

scope
spiking E/I assembly learning model
claim_text
Recurrent spiking network with biologically realistic PV, SST and VIP populations learns excitatory-inhibitory neuronal assemblies; VIP disinhibition gates assembly recruitment.
section_id
section_12
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json
review_repo
ComputationalReviewVIP
section_ref
wiki_page:computationalreviewvip-12-computational-models
source_kind
review_finding
source_path
evidence/section_12_evidence_package.json
study_system
spiking E/I assembly learning model
section_title
Computational Models of VIP Circuit Function
evidence_summary
Spiking network with STDP-like rules across multiple interneuron types; quantifies how VIP gates lateral inhibition during learning.
review_bundle_ref
analysis_bundle:ab-2ce40c33e827
replication_status
replicated_independent
review_package_ref
analysis_bundle:ab-2ce40c33e827
source_artifact_ref
wiki_page:computationalreviewvip-12-computational-models
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_12_evidence_package.json
commit_sha
95e761177f7d2ec565983d3307c14ec238f9677c
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewVIP
Raw fields (5)
raw_fields
{
  "n": null,
  "id": "cluster_11_finding_63",
  "doi": "10.7554/elife.59715",
  "pmid": "33900199",
  "year": "2021",
  "claim": "Recurrent spiking network with biologically realistic PV, SST and VIP populations learns excitatory-inhibitory neuronal assemblies; VIP disinhibition gates assembly recruitment.",
  "pmcid": "PMC8075581",
  "title": "Learning excitatory-inhibitory neuronal assemblies in recurrent networks.",
  "authors": "Mackwood O, Naumann LB, Sprekeler H.",
  "journal": "eLife",
  "cite_key": "Mackwood2021",
  "evidence": "Spiking network with STDP-like rules across multiple interneuron types; quantifies how VIP gates lateral inhibition during learning.",
  "effect_size": null,
  "text_access": "fulltext",
  "study_system": "spiking E/I assembly learning model",
  "_source_cluster": "cluster_11_computational_models",
  "replication_status": "replicated_independent",
  "_source_cluster_index": 62,
  "claim_source_sentence": "To investigate the effect of stimulus-specific inhibition in our network, we simulate the perturbation experiment of Chettih and Harvey, 2019 : First, we again expose the network to the stimulus set, with PV input and output plasticity in place to learn E/I assemblies.",
  "replication_evidence_dois": [
    "10.1016/j.neuron.2023.11.006",
    "10.1101/2025.05.13.653877",
    "10.1101/2024.09.30.615819",
    "10.1016/j.neuron.2018.03.037",
    "10.1162/netn_a_00427"
  ],
  "effect_size_source_sentence": null
}
source_refs
[
  "paper:paper-ce8a09f59a46"
]
source_span
To investigate the effect of stimulus-specific inhibition in our network, we simulate the perturbation experiment of Chettih and Harvey, 2019 : First, we again expose the network to the stimulus set, with PV input and output plasticity in place to learn E/I assemblies.
evidence_refs
[
  {
    "ref": "paper:paper-ce8a09f59a46"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}

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