Version history

{
  "scope": "mouse (Mus musculus); whole-brain CBGT loop",
  "claim_text": "Whole-mouse-brain anterograde mapping reveals six parallel cortico-basal ganglia-thalamic subnetworks (rather than three) that close back onto their originating corticostriatal neurons in a bona fide closed-loop topology.",
  "raw_fields": {
    "n": null,
    "doi": "10.1038/s41586-021-03993-3",
    "claim": "Whole-mouse-brain anterograde mapping reveals six parallel cortico-basal ganglia-thalamic subnetworks (rather than three) that close back onto their originating corticostriatal neurons in a bona fide closed-loop topology.",
    "cite_key": "Foster2021",
    "evidence": "Multi-synaptic anterograde viral tracing of striatal output via GPe, SNr, and thalamus across whole mouse brain; 29 striatal domains, 14 SNr domains, 36 GPe domains.",
    "effect_size": "6 parallel CBGT subnetworks; 14 SNr domains; 36 GPe domains; 29 striatal domains",
    "text_access": "fulltext",
    "study_system": "mouse (Mus musculus); whole-brain CBGT loop",
    "source_cluster_id": "cluster_01",
    "replication_status": "replication_unknown",
    "claim_source_sentence": "Previous efforts to refine the three-channel model have postulated a number of specific parallel subnetworks 1 , 11 .",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "Accordingly, we identify 14 SNr and 36 GPe domains and a direct cortico-SNr projection."
  },
  "section_id": "section_16",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_16_evidence_package.json",
  "effect_size": "6 parallel CBGT subnetworks; 14 SNr domains; 36 GPe domains; 29 striatal domains",
  "review_repo": "ComputationalReviewLoops",
  "section_ref": "wiki_page:computationalreviewloops-16",
  "source_kind": "review_finding",
  "source_path": "evidence/section_16_evidence_package.json",
  "source_refs": [
    "paper:paper-79995db40fc1"
  ],
  "source_span": "Previous efforts to refine the three-channel model have postulated a number of specific parallel subnetworks 1 , 11 .",
  "study_system": "mouse (Mus musculus); whole-brain CBGT loop",
  "evidence_refs": [
    {
      "ref": "paper:paper-79995db40fc1"
    }
  ],
  "section_title": "Synthesis: Reassessing the Generalized Loop Model 25 Years On",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
  },
  "evidence_summary": "Multi-synaptic anterograde viral tracing of striatal output via GPe, SNr, and thalamus across whole mouse brain; 29 striatal domains, 14 SNr domains, 36 GPe domains.",
  "review_bundle_ref": "analysis_bundle:ab-d49e54403ef9",
  "replication_status": "replication_unknown",
  "review_package_ref": "analysis_bundle:ab-d49e54403ef9",
  "source_artifact_ref": "wiki_page:computationalreviewloops-16",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_16_evidence_package.json",
  "commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}