Version history

{
  "scope": "In vivo mouse; miniaturized widefield voltage microscope with Voltron2",
  "claim_text": "A 16.4 g miniaturized widefield voltage-imaging microscope can record Voltron2 spikes in vivo at 530 Hz with peak-to-noise ratio >3 across a 250 µm field of view — concretely bounding the present-day yield/speed/FOV envelope of head-mounted voltage imaging.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1364/boe.576516",
    "claim": "A 16.4 g miniaturized widefield voltage-imaging microscope can record Voltron2 spikes in vivo at 530 Hz with peak-to-noise ratio >3 across a 250 µm field of view — concretely bounding the present-day yield/speed/FOV envelope of head-mounted voltage imaging.",
    "cite_key": "Saladrigas2026",
    "evidence": "Quantitative ceiling on freely-moving voltage imaging — directly relevant to cluster_14's discussion of what voltage imaging cannot yet measure.",
    "effect_size": "NA 0.6; 250 µm FOV; 1.3–1.6 mm working distance; 16.4 g; 530 Hz frame rate; SNR >3",
    "text_access": "abstract_only",
    "study_system": "In vivo mouse; miniaturized widefield voltage microscope with Voltron2",
    "argument_role": "supporting",
    "replication_status": "single-study",
    "claim_source_sentence": "We show it is capable of imaging <i>in vivo</i> voltage spikes from Voltron2 with a spike peak-to-noise ratio >3 at a framerate of 530 Hz.",
    "source_provenance_status": "non_substring_match",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "We present a miniaturized microscope designed for voltage imaging, with a numerical aperture of 0.6, a 250 µm field of view, and a 1.3-1.6 mm working distance that weighs 16.4 g."
  },
  "section_id": "section_16",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_16_evidence_package.json",
  "effect_size": "NA 0.6; 250 µm FOV; 1.3–1.6 mm working distance; 16.4 g; 530 Hz frame rate; SNR >3",
  "review_repo": "ComputationalReviewRecurrence",
  "section_ref": "wiki_page:computationalreviewrecurrence-16-synthesis",
  "source_kind": "review_finding",
  "source_path": "evidence/section_16_evidence_package.json",
  "source_refs": [
    "paper:paper-d123a7539f4f"
  ],
  "source_span": "We show it is capable of imaging <i>in vivo</i> voltage spikes from Voltron2 with a spike peak-to-noise ratio >3 at a framerate of 530 Hz.",
  "study_system": "In vivo mouse; miniaturized widefield voltage microscope with Voltron2",
  "evidence_refs": [
    {
      "ref": "paper:paper-d123a7539f4f"
    }
  ],
  "section_title": "16. Synthesis — which computational claims the mouse-cortex E→E empirical record actually supports, where the bottleneck observations are, and what an inhibition-free, single-species, basic-research analytic framing misses",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
  },
  "evidence_summary": "Quantitative ceiling on freely-moving voltage imaging — directly relevant to cluster_14's discussion of what voltage imaging cannot yet measure.",
  "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9",
  "replication_status": "single-study",
  "review_package_ref": "analysis_bundle:ab-d9c479db9be9",
  "source_artifact_ref": "wiki_page:computationalreviewrecurrence-16-synthesis",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_16_evidence_package.json",
  "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}