Version history

{
  "scope": "entorhinal cortex interneurons, in vitro dynamic clamp + computational model",
  "claim_text": "PV+ fast-firing basket cells are more likely to exhibit class 2 excitability with post-inhibitory rebound than other interneuron types, enabling more robust ING gamma synchronization in the presence of noise and heterogeneity",
  "raw_fields": {
    "n": 0,
    "doi": "10.1523/jneurosci.2601-15.2015",
    "claim": "PV+ fast-firing basket cells are more likely to exhibit class 2 excitability with post-inhibitory rebound than other interneuron types, enabling more robust ING gamma synchronization in the presence of noise and heterogeneity",
    "evidence": "Computational modeling and dynamic clamp experiments in entorhinal cortical interneurons",
    "effect_size": "Robustness to heterogeneity increases as average participation approximates physiological levels (~every other cycle)",
    "text_access": "abstract_only",
    "study_system": "entorhinal cortex interneurons, in vitro dynamic clamp + computational model",
    "replication_status": "single study",
    "claim_source_sentence": "PV+ cells were much more likely to display both PIR and autapse-induced firing than GAD2+ cells, supporting the view that PV+ fast-firing basket cells are more likely to exhibit class 2 excitability than other types of inhibitory interneurons.",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "This results in much greater robustness to heterogeneity that actually increases as the average participation in spikes per cycle approximates physiological levels."
  },
  "section_id": "section_07_evidence_package",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_07_evidence_package.json",
  "effect_size": "Robustness to heterogeneity increases as average participation approximates physiological levels (~every other cycle)",
  "review_repo": "ComputationalReviewPV",
  "section_ref": "wiki_page:computationalreviewpv-07",
  "source_kind": "review_finding",
  "source_path": "evidence/section_07_evidence_package.json",
  "source_refs": [
    "paper:paper-cde5b8227f4d"
  ],
  "source_span": "PV+ cells were much more likely to display both PIR and autapse-induced firing than GAD2+ cells, supporting the view that PV+ fast-firing basket cells are more likely to exhibit class 2 excitability than other types of inhibitory interneurons.",
  "study_system": "entorhinal cortex interneurons, in vitro dynamic clamp + computational model",
  "evidence_refs": [
    {
      "ref": "paper:paper-cde5b8227f4d"
    }
  ],
  "section_title": "Local Circuit Motifs: Perisomatic Inhibition, Feedback, and Feedforward",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
  },
  "evidence_summary": "Computational modeling and dynamic clamp experiments in entorhinal cortical interneurons",
  "review_bundle_ref": "analysis_bundle:ab-e6261c8263e7",
  "replication_status": "single study",
  "review_package_ref": "analysis_bundle:ab-e6261c8263e7",
  "source_artifact_ref": "wiki_page:computationalreviewpv-07",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV/blob/df9fc7e8d455b084152c9d713558dae0013cef21/evidence/section_07_evidence_package.json",
  "commit_sha": "df9fc7e8d455b084152c9d713558dae0013cef21",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewPV"
}