Details

scope
Awake mouse visual cortex; mesoscale two-photon calcium imaging
section_id
section_16
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_16_evidence_package.json
effect_size
>10,000 neurons simultaneously recorded in mouse visual cortex
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-16-synthesis
source_kind
review_finding
source_path
evidence/section_16_evidence_package.json
study_system
Awake mouse visual cortex; mesoscale two-photon calcium imaging
section_title
16. Synthesis — which computational claims the mouse-cortex E→E empirical record actually supports, where the bottleneck observations are, and what an inhibition-free, single-species, basic-research analytic framing misses
evidence_summary
Foundational large-scale 2P result motivating multidimensional analyses of mouse-cortex population codes; large-N enabled by mesoscope.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
single-study
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-16-synthesis
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_16_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (6)
claim_text
Recording more than 10,000 neurons in awake mouse visual cortex shows that spontaneous activity reliably encodes a high-dimensional latent state related to ongoing behavior across the forebrain, and that sensory inputs add stimulus representations in orthogonal dimensions rather than interrupting the ongoing signal.
raw_fields
{
  "n": 10000,
  "doi": "10.1126/science.aav7893",
  "claim": "Recording more than 10,000 neurons in awake mouse visual cortex shows that spontaneous activity reliably encodes a high-dimensional latent state related to ongoing behavior across the forebrain, and that sensory inputs add stimulus representations in orthogonal dimensions rather than interrupting the ongoing signal.",
  "cite_key": "Stringer2019b",
  "evidence": "Foundational large-scale 2P result motivating multidimensional analyses of mouse-cortex population codes; large-N enabled by mesoscope.",
  "effect_size": ">10,000 neurons simultaneously recorded in mouse visual cortex",
  "text_access": "abstract_only",
  "study_system": "Awake mouse visual cortex; mesoscale two-photon calcium imaging",
  "argument_role": "supporting",
  "replication_status": "single-study",
  "claim_source_sentence": "Recording more than 10,000 neurons in mouse visual cortex, we observed that spontaneous activity reliably encoded a high-dimensional latent state, which was partially related to the mouse's ongoing behavior and was represented not just in visual cortex but also across the forebrain.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "Recording more than 10,000 neurons in mouse visual cortex, we observed that spontaneous activity reliably encoded a high-dimensional latent state, which was partially related to the mouse's ongoing behavior and was represented not just in visual cortex but also across the forebrain."
}
source_refs
[
  "paper:paper-d69a4ecd49f6"
]
source_span
Recording more than 10,000 neurons in mouse visual cortex, we observed that spontaneous activity reliably encoded a high-dimensional latent state, which was partially related to the mouse's ongoing behavior and was represented not just in visual cortex but also across the forebrain.
evidence_refs
[
  {
    "ref": "paper:paper-d69a4ecd49f6"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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