In the mouse medial prefrontal cortex, the dorsal peduncular area (DP) — divide…

In the mouse medial prefrontal cortex, the dorsal peduncular area (DP) — divided into deep (DPd) and superficial (DPs) layers — and the infralimbic area form a visceromotor cortex that projects directly to hypothalamic and brainstem autonomic centers, while integrating diverse cortical inputs as a hub.

{
  "n": null,
  "doi": "10.1038/s41586-025-09360-w",
  "claim": "In the mouse medial prefrontal cortex, the dorsal peduncular area (DP) — divided into deep (DPd) and superficial (DPs) layers — and the infralimbic area form a visceromotor cortex that projects directly to hypothalamic and brainstem autonomic centers, while integrating diverse cortical inputs as a hub.",
  "cite_key": "Hintiryan2025",
  "evidence": "Integrated neuroanatomical, electrophysiological and behavioural mapping of mouse medial prefrontal cortex producing a mesoscale MPF connectome focused on DP.",
  "effect_size": null,
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  "study_system": "mouse medial prefrontal cortex, mesoscale connectome",
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  "claim_source_sentence": "We identify its deep (DPd) and superficial (DPs) layers, along with the infralimbic area, as major components of the visceromotor cortex that directly project to hypothalamic and brainstem structures to govern neuroendocrine, sympathetic and parasympathetic output.",
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We identify its deep (DPd) and superficial (DPs) layers, along with the infralimbic area, as major components of the visceromotor cortex that directly project to hypothalamic and brainstem structures to govern neuroendocrine, sympathetic and parasympathetic output.

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