Version history

{
  "scope": "mouse dmPFC; in vivo microendoscopic GCaMP6f imaging",
  "claim_text": "In mouse dmPFC during a goal-directed sensory discrimination task, VIP+ and PV+ interneurons preferentially signal punishment-related events (with VIP responding strongly to punishment) while SST+ neurons preferentially signal lick-bout/reward onset — providing distinct cell-type-specific task signals.",
  "raw_fields": {
    "n": "VIP n=390, PV n=243, SST n=388, PYR n=631 task-modulated cells",
    "doi": "10.1016/j.neuron.2015.06.021",
    "claim": "In mouse dmPFC during a goal-directed sensory discrimination task, VIP+ and PV+ interneurons preferentially signal punishment-related events (with VIP responding strongly to punishment) while SST+ neurons preferentially signal lick-bout/reward onset — providing distinct cell-type-specific task signals.",
    "title": null,
    "cite_key": "Pinto2015",
    "evidence": "Cellular-resolution microendoscopic Ca2+ imaging in mouse dmPFC during a sensory discrimination task with rewards and punishments.",
    "effect_size": "Task-modulated fraction: PV 95.3%, SST 96.9%, VIP 81.2%, PYR 77.3%; CC for VIP=0.31±0.01 (n=390), PYR=0.24±0.01 (n=631).",
    "text_access": "fulltext",
    "study_system": "mouse dmPFC; in vivo microendoscopic GCaMP6f imaging",
    "_source_cluster": "cluster_05_synaptic_connectivity",
    "replication_status": "single-study",
    "_source_cluster_index": 34,
    "claim_source_sentence": "Significant PN responses were found in VIP + , PV + , and PYR neurons ( ; p < 10 −10 , signed rank test), but not in SST + neurons (p = 0.61), while RW responses were larger in PV + neurons than all other cell types.",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": "However, the percentage of neurons that were significantly modulated by the task (p < 0.01, 3-way ANOVA, see Experimental Procedures) differed across cell types, higher for PV + (95.3%) and SST + (96.9%) than for VIP + (81.2%) and PYR (77.3%) neurons."
  },
  "section_id": "section_06",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_06_evidence_package.json",
  "effect_size": "Task-modulated fraction: PV 95.3%, SST 96.9%, VIP 81.2%, PYR 77.3%; CC for VIP=0.31±0.01 (n=390), PYR=0.24±0.01 (n=631).",
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-06-synaptic-properties",
  "source_kind": "review_finding",
  "source_path": "evidence/section_06_evidence_package.json",
  "source_refs": [
    "paper:paper-6fb6c7efe883"
  ],
  "source_span": "Significant PN responses were found in VIP + , PV + , and PYR neurons ( ; p < 10 −10 , signed rank test), but not in SST + neurons (p = 0.61), while RW responses were larger in PV + neurons than all other cell types.",
  "study_system": "mouse dmPFC; in vivo microendoscopic GCaMP6f imaging",
  "evidence_refs": [
    {
      "ref": "paper:paper-6fb6c7efe883"
    }
  ],
  "section_title": "Synaptic Properties and Connectivity",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "Cellular-resolution microendoscopic Ca2+ imaging in mouse dmPFC during a sensory discrimination task with rewards and punishments.",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "single-study",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-06-synaptic-properties",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_06_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}