Version history

{
  "scope": "mouse forelimb M1 in vitro",
  "claim_text": "In mouse motor cortex, layer-6 corticothalamic neurons make strong reciprocal connections with other CT and IT neurons but strikingly little excitatory connectivity to PT pyramidal-tract neurons, and M1-CT and ventrolateral thalamocortical neurons are remarkably unconnected in either direction — contrasting with sensory cortex.",
  "raw_fields": {
    "n": 0,
    "doi": "10.1523/jneurosci.4023-14.2015",
    "claim": "In mouse motor cortex, layer-6 corticothalamic neurons make strong reciprocal connections with other CT and IT neurons but strikingly little excitatory connectivity to PT pyramidal-tract neurons, and M1-CT and ventrolateral thalamocortical neurons are remarkably unconnected in either direction — contrasting with sensory cortex.",
    "cite_key": "Yamawaki2015",
    "evidence": "Multi-method circuit analysis (laser scanning photostimulation + paired patch + optogenetics) in mouse forelimb M1.",
    "effect_size": "",
    "text_access": "abstract_only",
    "study_system": "mouse forelimb M1 in vitro",
    "source_cluster_id": "cluster_01",
    "replication_status": "replication_unknown",
    "claim_source_sentence": "Stimulating and recording from CT, intratelencephalic (IT), and pyramidal tract (PT) projection neurons, we found strong CT↔ CT and CT↔ IT connections; however, CT→IT connections were limited to IT neurons in layer 6, not 5B. There was strikingly little CT↔ PT excitatory connectivity. ... we found that M1-CT neurons and thalamocortical neurons in the ventrolateral (VL) nucleus were remarkably unconnected in either direction.",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": null
  },
  "section_id": "section_01",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_01_evidence_package.json",
  "effect_size": "",
  "review_repo": "ComputationalReviewLoops",
  "section_ref": "wiki_page:computationalreviewloops-01",
  "source_kind": "review_finding",
  "source_path": "evidence/section_01_evidence_package.json",
  "source_refs": [
    "paper:paper-77ff3f69a352"
  ],
  "source_span": "Stimulating and recording from CT, intratelencephalic (IT), and pyramidal tract (PT) projection neurons, we found strong CT↔ CT and CT↔ IT connections; however, CT→IT connections were limited to IT neurons in layer 6, not 5B. There was strikingly little CT↔ PT excitatory connectivity. ... we found that M1-CT neurons and thalamocortical neurons in the ventrolateral (VL) nucleus were remarkably unconnected in either d...",
  "study_system": "mouse forelimb M1 in vitro",
  "evidence_refs": [
    {
      "ref": "paper:paper-77ff3f69a352"
    }
  ],
  "section_title": "Introduction: Swanson's Loop Hypothesis and Its Intellectual Lineage",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
  },
  "evidence_summary": "Multi-method circuit analysis (laser scanning photostimulation + paired patch + optogenetics) in mouse forelimb M1.",
  "review_bundle_ref": "analysis_bundle:ab-d49e54403ef9",
  "replication_status": "replication_unknown",
  "review_package_ref": "analysis_bundle:ab-d49e54403ef9",
  "source_artifact_ref": "wiki_page:computationalreviewloops-01",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops/blob/0632aae8abc141909207fe91f6349b9e36489c3b/evidence/section_01_evidence_package.json",
  "commit_sha": "0632aae8abc141909207fe91f6349b9e36489c3b",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewLoops"
}