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- Live5/17/2026, 4:35:28 PM
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{ "scope": "Mouse, ACC→VIS and ACC→SC projections; 2P imaging + optogenetics", "claim_text": "Mouse anterior cingulate (ACC) outputs to visual cortex and to superior colliculus operate as distinct sensorimotor circuits: ACC→VIS enhances sensory processing of visual cues, ACC→SC coordinates motor response selection.", "raw_fields": { "n": null, "doi": "10.1038/s41467-020-19772-z", "claim": "Mouse anterior cingulate (ACC) outputs to visual cortex and to superior colliculus operate as distinct sensorimotor circuits: ACC→VIS enhances sensory processing of visual cues, ACC→SC coordinates motor response selection.", "cite_key": "Huda2020", "evidence": "Projection-specific two-photon calcium imaging and optogenetic manipulation of mouse ACC→VIS vs ACC→SC outputs during a two-choice visually guided task.", "effect_size": "ACC→SC reduces innate response bias of SC and coordinates motor responses; ACC→VIS facilitates sensory cue processing (qualitative).", "text_access": "abstract_only", "study_system": "Mouse, ACC→VIS and ACC→SC projections; 2P imaging + optogenetics", "argument_role": "supporting", "replication_status": "single-study", "claim_source_sentence": "In contrast, ACC outputs to the visual cortex facilitate sensory processing of visual cues.", "source_provenance_status": "non_substring_match", "replication_evidence_dois": [], "effect_size_source_sentence": "Importantly, ACC outputs exert control by reducing the innate response bias of the superior colliculus." }, "section_id": "section_08", "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json", "effect_size": "ACC→SC reduces innate response bias of SC and coordinates motor responses; ACC→VIS facilitates sensory cue processing (qualitative).", "review_repo": "ComputationalReviewRecurrence", "section_ref": "wiki_page:computationalreviewrecurrence-08-cross-areal", "source_kind": "review_finding", "source_path": "evidence/section_08_evidence_package.json", "source_refs": [ "paper:paper-76648660797f" ], "source_span": "In contrast, ACC outputs to the visual cortex facilitate sensory processing of visual cues.", "study_system": "Mouse, ACC→VIS and ACC→SC projections; 2P imaging + optogenetics", "evidence_refs": [ { "ref": "paper:paper-76648660797f" } ], "section_title": "8. Cross-areal mouse cortico-cortical excitatory connectivity — hierarchical feedforward and feedback as recurrent loops at the network level; Allen Mouse Connectivity Atlas anchored views", "source_policy": { "mode": "public_source_pointer_with_short_context", "notes": [ "Local review repositories are read-only inputs.", "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose." ], "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }, "evidence_summary": "Projection-specific two-photon calcium imaging and optogenetic manipulation of mouse ACC→VIS vs ACC→SC outputs during a two-choice visually guided task.", "review_bundle_ref": "analysis_bundle:ab-d9c479db9be9", "replication_status": "single-study", "review_package_ref": "analysis_bundle:ab-d9c479db9be9", "source_artifact_ref": "wiki_page:computationalreviewrecurrence-08-cross-areal", "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json", "commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f", "created_by": "persona-jerome-lecoq-gbo-neuroscience", "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence" }