Details

scope
Mouse, ACC→VIS and ACC→SC projections; 2P imaging + optogenetics
claim_text
Mouse anterior cingulate (ACC) outputs to visual cortex and to superior colliculus operate as distinct sensorimotor circuits: ACC→VIS enhances sensory processing of visual cues, ACC→SC coordinates motor response selection.
section_id
section_08
source_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json
effect_size
ACC→SC reduces innate response bias of SC and coordinates motor responses; ACC→VIS facilitates sensory cue processing (qualitative).
review_repo
ComputationalReviewRecurrence
section_ref
wiki_page:computationalreviewrecurrence-08-cross-areal
source_kind
review_finding
source_path
evidence/section_08_evidence_package.json
source_span
In contrast, ACC outputs to the visual cortex facilitate sensory processing of visual cues.
study_system
Mouse, ACC→VIS and ACC→SC projections; 2P imaging + optogenetics
section_title
8. Cross-areal mouse cortico-cortical excitatory connectivity — hierarchical feedforward and feedback as recurrent loops at the network level; Allen Mouse Connectivity Atlas anchored views
evidence_summary
Projection-specific two-photon calcium imaging and optogenetic manipulation of mouse ACC→VIS vs ACC→SC outputs during a two-choice visually guided task.
review_bundle_ref
analysis_bundle:ab-d9c479db9be9
replication_status
single-study
review_package_ref
analysis_bundle:ab-d9c479db9be9
source_artifact_ref
wiki_page:computationalreviewrecurrence-08-cross-areal
origin_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence/blob/79ce062d54a924ce05953ec90aa9d26044d2b48f/evidence/section_08_evidence_package.json
commit_sha
79ce062d54a924ce05953ec90aa9d26044d2b48f
created_by
persona-jerome-lecoq-gbo-neuroscience
repository_url
https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence
Raw fields (4)
raw_fields
{
  "n": null,
  "doi": "10.1038/s41467-020-19772-z",
  "claim": "Mouse anterior cingulate (ACC) outputs to visual cortex and to superior colliculus operate as distinct sensorimotor circuits: ACC→VIS enhances sensory processing of visual cues, ACC→SC coordinates motor response selection.",
  "cite_key": "Huda2020",
  "evidence": "Projection-specific two-photon calcium imaging and optogenetic manipulation of mouse ACC→VIS vs ACC→SC outputs during a two-choice visually guided task.",
  "effect_size": "ACC→SC reduces innate response bias of SC and coordinates motor responses; ACC→VIS facilitates sensory cue processing (qualitative).",
  "text_access": "abstract_only",
  "study_system": "Mouse, ACC→VIS and ACC→SC projections; 2P imaging + optogenetics",
  "argument_role": "supporting",
  "replication_status": "single-study",
  "claim_source_sentence": "In contrast, ACC outputs to the visual cortex facilitate sensory processing of visual cues.",
  "source_provenance_status": "non_substring_match",
  "replication_evidence_dois": [],
  "effect_size_source_sentence": "Importantly, ACC outputs exert control by reducing the innate response bias of the superior colliculus."
}
source_refs
[
  "paper:paper-76648660797f"
]
evidence_refs
[
  {
    "ref": "paper:paper-76648660797f"
  }
]
source_policy
{
  "mode": "public_source_pointer_with_short_context",
  "notes": [
    "Local review repositories are read-only inputs.",
    "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
  ],
  "source_commit_sha": "79ce062d54a924ce05953ec90aa9d26044d2b48f",
  "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewRecurrence"
}

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