Version history

{
  "scope": "human, mouse, rat",
  "claim_text": "Together, these results indicate that VIP+ INs in the Tcf4 +/ tr mice show increased input resistance and reduced frequency of sEPSCs which indicates the excitatory drive onto VIP+ INs is reduced, and this may be slightly counterbalanced by an increase sensitivity/responsiveness to synaptic inputs d",
  "raw_fields": {
    "n": 0,
    "doi": "10.1038/s41380-023-02248-z",
    "claim": "Together, these results indicate that VIP+ INs in the Tcf4 +/ tr mice show increased input resistance and reduced frequency of sEPSCs which indicates the excitatory drive onto VIP+ INs is reduced, and this may be slightly counterbalanced by an increase sensitivity/responsiveness to synaptic inputs d",
    "title": null,
    "cite_key": "Chen2023b",
    "evidence": "Reported in study using human, mouse, rat.",
    "effect_size": null,
    "text_access": "fulltext",
    "study_system": "human, mouse, rat",
    "_source_cluster": "cluster_10_species_disease",
    "replication_status": "multiple_database_indexed",
    "_source_cluster_index": 0,
    "claim_source_sentence": "Together, these results indicate that VIP+ INs in the Tcf4 +/ tr mice show increased input resistance and reduced frequency of sEPSCs which indicates the excitatory drive onto VIP+ INs is reduced, and this may be slightly counterbalanced by an increase sensitivity/responsiveness to synaptic inputs due to the increased input resistance.",
    "replication_evidence_dois": [],
    "effect_size_source_sentence": null
  },
  "section_id": "section_11",
  "source_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_11_evidence_package.json",
  "effect_size": null,
  "review_repo": "ComputationalReviewVIP",
  "section_ref": "wiki_page:computationalreviewvip-11-disease-translational",
  "source_kind": "review_finding",
  "source_path": "evidence/section_11_evidence_package.json",
  "source_refs": [
    "paper:paper-bcba2772b0e0"
  ],
  "source_span": "Together, these results indicate that VIP+ INs in the Tcf4 +/ tr mice show increased input resistance and reduced frequency of sEPSCs which indicates the excitatory drive onto VIP+ INs is reduced, and this may be slightly counterbalanced by an increase sensitivity/responsiveness to synaptic inputs due to the increased input resistance.",
  "study_system": "human, mouse, rat",
  "evidence_refs": [
    {
      "ref": "paper:paper-bcba2772b0e0"
    }
  ],
  "section_title": "Species Differences, Human Relevance, and Disease",
  "source_policy": {
    "mode": "public_source_pointer_with_short_context",
    "notes": [
      "Local review repositories are read-only inputs.",
      "SciDEX stores paper metadata, structured evidence, file pointers, and short citation contexts; it does not copy full review prose."
    ],
    "source_commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
    "source_repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
  },
  "evidence_summary": "Reported in study using human, mouse, rat.",
  "review_bundle_ref": "analysis_bundle:ab-2ce40c33e827",
  "replication_status": "multiple_database_indexed",
  "review_package_ref": "analysis_bundle:ab-2ce40c33e827",
  "source_artifact_ref": "wiki_page:computationalreviewvip-11-disease-translational",
  "origin_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP/blob/95e761177f7d2ec565983d3307c14ec238f9677c/evidence/section_11_evidence_package.json",
  "commit_sha": "95e761177f7d2ec565983d3307c14ec238f9677c",
  "created_by": "persona-jerome-lecoq-gbo-neuroscience",
  "repository_url": "https://github.com/AllenNeuralDynamics/ComputationalReviewVIP"
}